Despite the research and development is still no method of complete deliverance from diabetes mellitus type 1 or 2. However, the disease may successfully control with the help of doctors and healthy lifestyle, which includes compliance with certain diet and availability of physical activity. Expert help can be obtained in Israel in the treatment of diabetes.

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In a number of cases of diabetes mellitus type 2 fairly significant amount of physical exercise and a healthy diet. In other situations, necessary medications that stimulate the pancreas to produce more insulin or to cope better with the amount of glucose in the blood.

With this form of the disease type 1 body is unable to produce the necessary hormones, so it needs regular injections. Sometimes in type 2 diabetes may also require insulin injections.

If there is a gestational diabetes during pregnancy, proper diet and the necessary motor activity may be enough for some women to cope with the disease. While others may need medication.

Goals of treatment of diabetes in Israel

  1. Maintain blood glucose levels as close to normal through diet, exercise and drug therapy.
  2. Coordinate the amount of cholesterol through diet and, if provided, of medical preparations.
  3. To control blood pressure, since the disease creates an increased risk for heart health.

Lifestyle is also important in this disease, so the following steps are necessary:

  1. Plan timely, balanced diet in order to avoid fluctuations in blood sugar levels.
  2. Maintain the necessary level of physical activity.
  3. Make timely preparations.
  4. Control the level of glucose and pressure at home.

Attend regular doctor and take the test on glycohemoglobin (HbA1c), a blood test that measures the content likozilirovannogo hemoglobin in the blood. Thanks to him, you can find out the average amount of sugar in the past six - twelve weeks.

Healthy diet in the treatment of diabetes in Israel

In spite of the existing opinion, there is a particular diet for a given ailment. However, it is important that the basis of the diet were products rich in fiber - fruits, whole grains and vegetables.

It is necessary to reduce animal and refined foods as well - with high amounts of sugar. Significant importance is such a thing as the glycemic index. It reflects the rate at which digested food increases blood sugar. Selection of products with a low index will help maintain stable blood glucose levels.

Nutritionist in Israel will help to develop a nutrition program based preferences in diet and lifestyle features. Also, teach, how to coordinate the amount of carbohydrate consumption, quantity and time of admission to the blood sugar level was stable.

Medicines for diabetes mellitus type 1

In this type of disease require daily injections of insulin, at least twice a day. To do this, you must learn this process, that may at first seem like a daunting task, but it soon becomes routine.

There is the possibility of using a specially designed device - insulin pump according to the pre-exposed program, which is being developed together with the doctor. This equipment is attached to the body, the needle catheter is inserted under the skin and is secured with a patch on the abdomen, and the device connected to the catheter, located on the belt. Hormone administered by remote control. This is an advanced alternative to injections by syringe or pen. In addition, the pump controls the level of glucose and calculates the amount of carbohydrates. There are more modernized development.

In the pathology of type 1 must be checked by a blood glucose meter to 4 times per day.

Treatment of diabetes type 2 in Israel

Medicated preparations for this type of disease work in different ways to stabilize the sugar content:

  1. Enlarge hormone synthesis.
  2. Reduce the absorption of sugar in the gut.
  3. Improve the ability of the body to apply pancreatic hormone.
  4. Reduce glucose production in the liver and increase insulin resistance.
  5. Pancreatic hormone production increase and decrease the synthesis of sugars in the liver.

In the treatment of diabetes in Israel used the following types of drugs.

  1. Metformin (Glucophage) increases the sensitivity of tissues to the body of protein and peptide hormone, contributing to its more efficient use. Furthermore, it suppresses hepatic glucose synthesis. Possible side effects may include nausea and diarrhea, usually disappear after adaptation of the organism. Glucose drug does not reduce to this doctor recommends lifestyle changes - to get rid of excess weight, increase physical activity. If this is not enough, added to other medications.
  2. sulfonylurea drugs help the body produce more insulin. Examples of this class of drugs include glyburide, glipizide, glimepiride. Possible side effects - low blood sugar and weight gain.
  3. Meglitinides (repaglinide, nateglinide) operate as the above mentioned drugs, induce the body to produce more insulin, but they are faster and do not remain active in the body so long. At their reception there is a possibility of weight gain and the risk of hypoglycemia, but to a lesser extent than in the group of sulfonylureas.
  4. Thiazolidinediones (Avandia, pioglitazone), like metformin, these medications increase the sensitivity of tissues to insulin. This class of drugs is associated with an increase in body weight and other more serious side effects such as increased risk of heart failure and fractures. Because of the undesirable manifestations of these medications are not regarded as medicine "first line".
  5. DPP-4 inhibitors (sitagliptin, saxagliptin, linagliptin) help to reduce blood sugar levels, but the effect is not very strong. Do not cause weight gain.
  6. GLP 1 receptor agonists (exenatide, liraglutide) contribute to decrease in blood sugar levels, although not as strongly as sulfonylureas. Possible side effects include nausea and an increased risk of pancreatitis.
  7. SGLT2 inhibitors (canagliflozin (Invokana), farxiga (dapagliflozin)) - the newest drugs for diabetes on the market. They do not allow glucose, which has already been filtered out by the kidneys, be reabsorbed back into the blood, sugar excreted in the urine. Among the negative phenomena of reception mark the development of yeast infections and urinary tract infections.

Besides the aforementioned medicaments To prevent heart disease and blood vessels can prescribe drugs that reduce the amount of cholesterol and blood pressure.

Precautionary measures

A good idea is considered to be wearing the bracelet alerts indicating diabetes. This can be useful in case of severe hypoglycemic events, an accident, a person is not able to explain anything. Hypoglycemic episodes can often be identified as drunkenness. If not treated promptly they can lead to a coma. Plus in a high stress is necessary to control blood sugar levels, it can be done in emergency situations medical staff providing assistance.

Alternative medicine in the treatment of diabetes in Israel

As alternative medicine should not be used alone for the treatment of this disease. Be sure to tell your doctor about the use of any new approaches. Biofeedback, meditation, hypnosis and yoga reduces levels of stress hormones that stabilizes glucose levels and reduces the need for insulin. Biofeedback (BFB methods) also increases the blood circulation in the extremities, reducing the risk of amputation.

Transplantation of islet cells for the treatment of diabetes in Israel

Relatively recently it became possible in type 1 diabetes produce healthy pancreas transplant cells borrowed from a deceased donor, in the patient's liver. New cells begin to synthesize protein and peptide hormone, normalizes sugar content.

Indications for transplantation

Treated patients in the age group from 18 to 65 years with a diagnosis of type 1 diabetes, the duration of which is more than five years, with the presence of complications - recurring episodes of loss of consciousness due to insulin deficiency and the initial symptoms of the kidney.

Advantages of this procedure:

  1. There is no need to control blood sugar levels and daily insulin injections. Although only a few people can not completely get rid of this one year after surgery.
  2. There is more freedom in planning the diet.
  3. Operation to prevent the development of serious complications.

transplant risks

The biggest problem - the likelihood of rejection of donor cells. The patient's immune system recognizes the donor tissue as "alien" and is trying to destroy. Therefore, throughout life needs to be taking drugs to suppress the immune response and prevent rejection. Many of them have serious adverse consequences. In addition, there are suspicions during long-term treatment of immunosuppressive drugs to increase the risk of oncology.

Performance indicators

The procedure was developed in the sixties of the twentieth century, first tested - in the nineties. However, the efficiency rate was only eight percent.

At the end of the 90s in the University of Alberta in Canada, scientists have upgraded the technology of collecting and preparing the cells for transplantation and immunosuppressive drugs have improved and achieved 100% success rate. This procedure is called the "Edmonton Protocol", its results are still being studied.

Research is currently focused on two main areas:

  1. To collect the necessary number of cells for the procedure, because there is a serious problem. It takes about 1 million islet cells, which corresponds to two of the pancreas. The need to exceed the existing capabilities, so researchers are working with other sources - embryonic tissues and animals (pigs) - trying to re-create them in the lab.
  2. Prevent rejection process - developed advanced drugs. Significant progress has been made over the past fifteen years - the use of new drugs - of rapamycin and tacrolimus (FK506) with fewer adverse effects. One of the latest developments is the use of a special gel coating cell immunity that prevents recognize them.

Transplantation of islet cells is currently still regarded as experimental, respectively, it is not publicly available. It is therefore important to choose a medical center, which is the necessary equipment, highly qualified medical staff and expertise in the field of transplantation.

Successful transplant can significantly improve the quality of life of patients with diabetes. But researchers do not call this method a real opportunity to get rid of the disease.

Insulin therapy in the treatment of diabetes in Israel

In diabetes, where there is a deficiency in insulin (hormone peptide), are assigned regular injections or use an insulin pump. This hormone is necessary for the absorption of glucose, thanks to him in the body is controlled by the level. There are many types of insulin to treat diabetes.

In the past, insulin was used as a last resort, but today, because of the advantages in most cases it is prescribed before.

Insulin analog - human hormone variant, which is used for chemical engineering techniques.

Indications for insulin:

  1. Type 1 diabetes. To control the disease using only medication - insulin.
  2. Type 2 diabetes. Insulin may designate either alone or in combination with other medicines.
  3. Gestational diabetes.

Types of insulin used to treat diabetes in Israel

Applies 6 main types.

  1. A rapid-acting analogues. The introduction of time, before or after eating. The duration of action of about 4 hours.
  2. Long-acting analogues. Introduction - once a day.
  3. Short-acting insulin. Introduction for 15-30 minutes before meals, duration - up to 8 hours.
  4. Insulin intermediate and long-acting. Used 1 or 2 times as monotherapy or in combination of short-acting insulin / Fast analogue. Duration - 30 hours.
  5. Mixed insulin combines short insulin and intermediate-acting.
  6. Mixed combines insulin analog intermediate acting and a fast analog.

Discuss the pros and cons of different drugs in the treatment of diabetes in Israel can be a specialist. Jointly decide which drug is best, after considering many factors. The choice will be affected:

  1. Individual body's response to insulin.

  2. Lifestyle: consumption of food, the amount of alcohol, the resulting exercise.

  3. The number of injections.

  4. The frequency of checking glucose levels.

  5. Age.

  6. Expenses and so forth.

For administration of the hormone using special syringes, pen cartridge for drug and doses (pump). From the place of administration depends on the terms of insulin. For the abdomen (stomach) is characterized by the highest rate of absorption of the hormone in the blood after it goes hand surface, thighs and buttocks.

By receiving the undesirable consequences include: low blood sugar (hypoglycemia); hypertrophy or enlargement of the body portion which has received a great number of injections; rash at the injection site or a hormone throughout the body (is rare).

The stem cells in the treatment of diabetes in Israel

Results of some studies have shown that people with newly diagnosed type 1 diabetes can help stem cell transplantation. It produces a kind of "reset" the immune system to its cells do not attack the pancreas. In Israel, the treatment of diabetes, there is the possibility of using this technique.

At this time, more research is needed to confirm the effectiveness of this method for long-term treatment of diabetes.