Chemotherapy for throat cancer Chemotherapy - a method of treatment which involves cytostatic drugs in the fight against malignant tumors.

Chemotherapy for throat cancer in Israeli hospitals used:

  • at the same time as radiation therapy - chemoradiotherapy;
  • to radiation therapy for tumor reduction, increasing the effectiveness of radiation;
  • for the purpose of disease control and symptom relief.

Chemotherapy drugs most commonly used to treat cancer of the larynx in the medical centers of Israel:

  • cisplatin (cisplatin)
  • 5-fluorouracil (5-Fluorouracil, also known as 5-FU)
  • docetaxel (docetaxel)

Other drugs that may be involved:

  • carboplatin (sarboplatin).
  • Taxol (paclitaxel)
  • bleomycin
  • ifosfamide.

The therapy may involve the use of a single drug or several in combination. Common schemes: cisplatin, 5-FU and cisplatin, docetaxel, and 5 FU. Also cytostatic combined with targeted therapy cetuximab.

Chemotherapy with throat cancer in Israel will provide excellent results of treatment. First, doctors used modern protocols of treatment, using a new generation of drugs, correctly selected medications and their dosage. Secondly, they involve various techniques that reduce the toxic effect of drugs on the body, reducing the amount of side effects. Our company, KC «Tlv.Hospital», will assist in the organization of treatment in Israel .

How is chemotherapy for cancer of the larynx?

The drug is administered to the body intravenously, through the short, fine cannula installed in a vein in the arm. Also used such devices as a central catheter or PICC line system.

Probably need to stay in hospital for several days. Chemotherapy is usually repeated every three weeks.


Certain cytotoxic agents, such as cisplatin, can enhance the efficacy of radiotherapy. Chemotherapy for cancer of the larynx is appointed simultaneously with irradiation and called chemoradiation. It is recommended instead of surgery as the primary treatment for some types of the disease. When a malignant tumor goes away completely under the influence of chemoradiotherapy, no other medication is no longer needed. But if the remains may be carried out surgery.

Chemoradiotherapy is also performed after surgery to reduce the chance of relapse. It is prescribed, if the cancer cells are detected at the remote edges during operation of samples, or if the cancer has other features that make it more likely the risk of the disease returning.

Common mode involves dose of cisplatin every three weeks (for a total of 3 doses) on the radiation time. Despite this, a combination of two of these procedures increases the immediate side effects and the risk of long-term effects.

Patients who can not tolerate chemoradiotherapy, administered with radiation therapy targeted agents cetuximab.

Targeted therapy of cancer of the larynx

Targeted drugs have anti-cancer effects, but works differently than chemotherapy for throat cancer.

Each tool has its effect, but they affect the growth or division of malignant cells.

The drug cetuximab (Erbitux®) is used in some cases, cancer of the larynx. The organism enters intravenously.

Cetuximab is aimed at specific proteins (receptors) on the surface of malignant cells. It prevents the growth and division of cells, but can also make the cancer cells more sensitive to radiation therapy.

Side effects of cetuximab are usually mild. Some people have flu-like symptoms - headache, fever, chills or dizziness. Patient in an Israeli hospital prescribed medications before the infusion, reduce the risk of these symptoms.

The most common side effect is a rash on the skin, usually in a mild form. However, sometimes there is a serious reaction in the area where the treatment was carried out. The doctor will advise how to care for the skin during treatment with cetuximab.

Potential side effects of chemotherapy for throat cancer

Treatment of cytostatic agents may cause unwanted effects. They can be controlled by medication, but in general, these symptoms disappear when the treatment ends. Not all drugs can cause side effects, and some patients have a very small number of them. Oncologist in an Israeli hospital to tell in detail what you can expect from taking specific drugs. Consider the frequently encountered adverse effects of therapy, and some techniques for reducing or eliminating them.

risk of infection

Receiving tsitosatikov can reduce the number of white blood cells that defend the body from various pathogens. If their level is low, the body will be prone to develop infections. This condition is known as neutropenia.

Need immediate assistance vaca if:

  • High temperature develops more 37.5˚C
  • The patient feels unwell, even at normal temperatures.
  • There is a chill.
  • There have been signs of an infection such as a cold, cough, frequent urination or diarrhea.

For the treatment of infections treatment is prescribed antibiotics. Before the beginning of each cycle of therapy the patient is losing blood test. The main task - to verify the contents of the white blood cells. Sometimes treatment time change if the number of white blood cells is reduced.

Anemia (decreased numbers of red blood cells)

Chemotherapy for cancer of the throat can reduce the level of red blood cells. This condition is called anemia, a person feels sluggish and tired. Shortness of breath may occur.

Anemia can be treated with blood transfusions. This will help the patient feel more energetic and reduce breathlessness.

Bruising and bleeding

Chemotherapy for cancer of the throat reduces blood platelet count. Platelets are cells which accelerate the clotting reaction. If you develop unexplained bruising or bleeding, such as from the nose, bleeding gums, skin rash, you need to immediately seek help from a specialist.


Certain cytotoxic agents have become a cause of nausea and even vomiting. Oncologist in an Israeli hospital appoints an agent for preventing these symptoms. If you do not help some medicines may be prescribed by others, there are several different types.


It is a common consequence of treatment. Should try to save power and save energy for the things that need to be done. Balance rest and physical activity (even short walks) can increase the energy level of the body.

Inflammation in the mouth

The mouth can become inflamed, may appear sores. Needs proper care, cleaning teeth (dentures) with a soft brush in the morning and evening after meals. It is important to drink plenty of fluids. Probably, doctors designate special rinses, medicines for prevention or treatment of oral infections, reduce pain.

loss of appetite

It happens that the patients during chemotherapy for throat cancer lose their appetite. Nutritionist in the Israeli clinic will advise on this problem, prescribe high-calorie drinks, while the appetite is not coming back.

Hair loss

Certain cytostatics lead to hair loss. In some cases, hair is lost completely, including eyebrows and eyelashes. In other cases, there is a partial loss or thinning. Not all drugs provoke this side effect.

Hair growth is resumed after 3-6 months after treatment. May change structure or shade of hair. The doctor will give advice on how to survive this condition and how to care for skin.

peripheral neuropathy

Numbness or tingling in the hands or feet occurs under the effect of cisplatin or docetaxel affecting nerves. It is important to notify your doctor if these symptoms appear. The condition usually improves slowly a few months after the end of therapy. Sometimes these manifestations take permanent.


A number of cytotoxic drugs cause diarrhea a few days after the cycle. They may be prescribed medication to help with this manifestation. It is necessary to drink plenty of fluids to make up for losses.

Pain in arms and legs

5-FU can cause redness or irritation of the palms of hands and soles of the feet. This condition is called palmoplantar erythema. Usually it is temporary. Apply moisturizing creams and odorless. You need to keep your hands and feet in the shade, avoid tight-fitting clothes - socks, shoes, gloves.

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