exposure of larynx cancerRadiation therapy - a method that uses high-energy rays to fight cancerous cells. During therapy, the patient does not feel the radiation, radiation therapy is similar to X-rays. During treatment, healthy cells can also be damaged, which will cause side effects. But this method can help kill cancer cells remaining after surgery, so you can avoid the recurrence of the disease in the future.

Medical service «Tlv.Hospital» offers professional organization of treatment of laryngeal cancer in Israel from the best specialists of the country.

Israeli doctors have successfully used in the treatment of cancer of the larynx modern methods of radiation therapy, such as radiation therapy and intensity modulated proton therapy. High skill radiation oncologists can accurately direct the radiation to the cancer of the larynx, which is delivered to it the maximum amount of radiation and ensuring minimal damage to healthy cells.

Cancer Radiotherapy larynx in Israel

Radiotherapy is often favored as a primary treatment of the disease in Israel. Most patients with early-stagelaryngeal cancerare cured by this method. Doctors may recommend radiation or endoscopic surgery. Both methods are effective and will help preserve the voice.

How well a radiotherapy for cancer of the larynx in a particular case depends on the amount and location of the tumors is determined by its depth germination in body tissue.

In the early stages of the disease treatment in most cases administered five times a week, from Monday to Friday for three - seven weeks. Radiation oncologist calculates the total dose of laryngeal cancer for the entire course, and then divides it into factions. This separation can reduce undesirable consequences of treatment.

Recent studies have revealed that chemotherapybefore radiotherapy can reduce the swelling and increase the radiation efficiency. Such a method is called neoadjuvant chemotherapy.

cancer radiation therapy after laryngeal surgery

This type of treatment is called adjuvant therapy. It helps to reduce the chance of the disease returning. Doctors in an Israeli hospital recommended radiation therapy aftersurgeryfor several reasons. The patient is prescribed irradiation of cancer of the larynx, if the disease can recur, because:

  1. The tumor is difficult to remove.
  2. The surgeon believes that the cancer cells remain in the body, because it was unable to obtain the necessary amount of surgical margins.
  3. Malignancy grown into the wall of the larynx.
  4. Cancer cells were found in lymph nodes or in an outer wall of the lymph nodes.

Treatment is carried out daily, Monday through Friday for four - six weeks - 20-30 fractions.

intensity modulated radiotherapy (IMRT)

Commonly used active form of radiotherapy where the radiation coincides in shape with the tumor. The dose in the treatment zone is different. This is effective when radiation therapy is given simultaneously on several different groups of lymph nodes. Since the effect is less healthy tissue, the patient will have fewer side effects, or they will be less severe.

IMRT may assign separately, or in combination with chemotherapy or biological therapy in locally advanced laryngeal cancer.

Studies show that IMRT reduces risk of such undesirable consequences as dryness in the oral cavity due to the lower dose of radiation therapy on the salivary gland.

proton therapy

Israel clinics can offer the most advanced method of exposure - proton therapy. It delivers high doses of radiation directly to the tumor, causing minimum damage to adjacent healthy tissues. This technology is available only in several medical centers around the world - an important tool in the treatment of head and neck tumors. In some patients, proton therapy provides better control of the disease with fewer side effects.

Radiation therapy with chemotherapy or biological therapy

In locally advanced laryngeal cancer at stages 3-4 it can be advised by radiotherapy with chemotherapy or biological therapy. Studies have found that sometimes these methods work best when used in combination. Cytostatics or targeted therapy may be useful in reducing the size of the tumor and in the control of disease.

Irradiation of laryngeal cancer to alleviate the symptoms of cancer

Radiation therapy can ease symptoms of the disease. This treatment is called palliative. The tumor is able to cause difficulty in swallowing, or pressing on the trachea, create difficulty in breathing.

Irradiation can reduce the size of tumors on time and to mitigate the symptoms of the disease and reduce pain. To achieve this goal is assigned a smaller number of treatments over several days.

Where and when is radiotherapy for cancer of the larynx?

Irradiation is carried out in the radiotherapy department. The patient visits the hospital five days a week, with a break for the weekend. The duration of treatment varies depending on the type and size of the tumor and treatment of the problem.

The process of planning irradiation of laryngeal cancer

Before starting treatment, the team of radiation oncologists involved careful planning external beam radiotherapy. Calculate the dose of irradiation and the treatment site is determined. The preparation process can take from 30 minutes to several hours. Patient undergoes CT with which a tumor is displayed and the structure around it.

Masks for radiotherapy

During working Irradiation of throat cancer by important IT is the That the patient to still lay. It helps keep it that mask or shell for the head and shoulders, to create an individual in the process of treatment planning. The mask makes it possible to breathe and see through it.

How is radiation therapy throat cancer?

Accelerators that provide exposure, is a large-sized machine. They may be in the same position or rotate around the body, delivering beams from different directions. Prior to treatment radiologists to explain in detail what to expect patient. The procedure takes a few minutes. It is important to be in the same position, which was developed by experts, each time to radiotherapy passed as efficiently as possible. After the doctors will help the patient in the correct position, the treatment begins.

External radiotherapy does not make the patient radioactive, it is perfectly safe when dealing with other people, including children, during the whole course of treatment.

Potential side effects

Unwanted effects of radiotherapy for cancer of the throat usually occur gradually. For most people, there are certain side effects in head and neck area. Usually, they get worse by the end of therapy. Within 2-3 weeks after treatment, they will be gradually reduced. This time period can be up to six weeks before the pain is completely gone.

Radiation therapy is a cancer of the larynx leads to pathological cell death, however, affect the healthy and in the treatment area, even if steps are taken to prevent this effect. On different tissues and organs of radiation may have a different effect.

Smoking and alcohol use during radiotherapy exacerbated side effects and reduces the effectiveness of treatment.

It is important to notify the team of doctors of the appearance of adverse effects of therapy, since many of them can be prevented or control them with medication and changes in diet or other measures. Specialists also estimate how serious side effects. In some cases, the procedure can be adjusted if side effects are severe.

  1. Skin reactions are a consequence of external radiation beam passing through the skin to the processing facility. The skin in this area may be red, become dry, or change color (darken or will look more tanned). Most of these reactions appear in the first two weeks of treatment and is held a few weeks after its completion. Doctors advise patients on care and protection of the skin during therapy, because it is more sensitive.
  2. Fatigue is often observed in patients during radiation therapy of cancer of the throat. The reason it can be depression, anemia, or poor appetite. During irradiation the body spends a lot of energy to heal itself, so the rest does not always help to get rid of this condition. The degree of symptoms may increase during therapy, after its terminations it is gradually disappearing.
  3. Radiation therapy can invoke stomatitis or oral mucositis as provoke irritation of oral mucous membranes, throat and esophagus. Effect develops the if the this Irradiation throat cancer Affects the oral cavity, or the if the chemotherapy is Performed simultaneously with the radiotherapy. Doctors advise about thorough and regular care that can prevent inflammation and reduce the risk of infection.
  4. Difficulty swallowing or heartburn may occur if the irradiation at throat cancer is exposed to the pharynx or gullet. Radiation can cause inflammation of the throat (pharyngitis) or esophagus (esophagitis), which will cause problems in the process of swallowing. Doctors in an Israeli hospital to offer antacids or painkillers. You may need to make changes in the diet - give preference to soft or liquid foods, start taking supplements. If the patient can not quite swallow food, it may take a temporary gastrostomy, through which the food will be delivered directly into the stomach.
  5. Xerostomia (insufficient secretion of saliva) may be the result of damage to the salivary glands in the mouth. This symptom appears in the first 2-3 weeks of treatment, may worsen during therapy. Recovery sometimes takes months or years. In some cases, the problem becomes a constant. It is important to follow the oral care instructions given by doctors.
  6. If the voice unit is within range of radiotherapy treatment, can change the voice, hoarseness. They are associated with edema and inflammation of the vocal cords (laryngitis). It is important to avoid alcohol and tobacco. Speech therapy using a variety of exercises and devices may be needed to strengthen the voice. Sometimes there is a change to vote on a permanent basis.
  7. Dysgeusia observed when radiation damages the salivary glands and taste buds of language that affects the perception of taste or smell. Taste buds are very sensitive to radiation, and the symptoms often occur during the first or second week of treatment. Doctors will give recommendations on this issue. State normalized after 1-3 months after the completion of radiation therapy.
  8. Caries is a late side effect of radiation therapy of the head and neck. Kserotomiya and radiation effects on tooth enamel increases the likelihood of tooth decay. Saliva helps cleanse the teeth and gums, so its deficiency increases the risk of tooth decay and gum disease. Before the start of irradiation of the larynx is often performed dental examination. It is very important good oral care. During this period should be avoided sugary products, since sugar contributes to the development of caries at lack of saliva. It may be assigned to treatment with fluoride, firming teeth. After therapy recommended regular visits to the dentist.
  9. Anorexia is a potential side effect of irradiation throat cancer. Contribute to this fatigue, changes in taste, difficulty swallowing, nausea and vomiting, accumulation of waste in the body due to malignant cells dying off. Loss of appetite can lead to malnutrition and weight loss. Good nutrition during and after radiation therapy is important for recovery. A nutritionist at the Israeli hospital can help. The patient will be given recommendations how to improve the appetite, are prescribed supplements.
  10. Radiation therapy in the neck capable to provoke hypothyroidism (underactive thyroid function). This body synthesizes hormones that help regulate and maintain many functions in the body. Symptoms of hypothyroidism include: fatigue, brittle nails, hair loss, dry skin. Possible changes in the menstrual cycle of women. Hypothyroidism usually develops after 3-4 years after treatment.
  11. Irradiation sometimes affects the lymph nodes to that shown lymphedema (fluid accumulation in the body). If the lymph nodes are not working properly, it accumulates fluid causing swelling of the face and neck. More likely this side effect in removing the lymph node during the operation.

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