liver transplantation Liver transplantation is a surgical procedure during which involves the exchange of the affected organ recipient to the whole body or a part of a healthy donor. For patients with liver cancer, this typeof surgery is one option disease treatment, but with the proviso that the tumor is limited only to one organ or metastasizes to adjacent areas of the body.

If you are considering surgery for a liver transplant abroad, our organization, medical service «Tlv.Hospital», will help in this task. We are a company of medical tourism in Israel and are professionally engaged in the diagnosis and treatment of the organization for 11 years.

Liver transplantation is carried out only in public clinics in the country. We select for you top notch surgeons and medical center, which will provide the best care. All this will be done in the shortest possible time and at affordable rates. We will make every effort that has been achieved the expected results.

You can learn more about the features of the Israeli health care and treatment of foreign nationals in the country's hospitals:

  1. Is for What medical tourism Culture in Israel is being of Treated without intermediaries
  2. The public and the private Clinic - Possibility for the States Foreign Tourists

Who is a candidate for a liver transplant in Israel?

Only a small number of patients who were diagnosed with the disease can be cured with the help of the surgical procedure, due to a number of indications and contraindications.

Transplant operation performed in patients with primary liver cancer if:

  • The organ is localized only one tumor (no more than 5 cm in width).
  • One revealed a malignant neoplasm (5-7 cm), which is stable for at least 6 months.
  • The liver was found 5 small cancers, each of which is not more than 3 cm in width.

Surgical intervention is not performed if:

  • Cancer metastasizes to adjacent organs and tissues.
  • There is a large and / or multiple cancerous growths.

The sources of organs for transplant liver

In Israel clinics can be performed as a full liver transplantation (from a dead donor) and partial (from a live person). Due to the fact that religious beliefs in the State provide some restrictions on the use of healthy body of a deceased person, in Israeli medical institutions often use the second type of transplant, although the country's legislation allows for a liver transplant, withdrawn posthumously.

liver transplantation

It carried out to treat patients with small tumors observed localized in a certain area of ​​the liver and in the absence of metastasis to the neighboring tissues. Before there is a suitable donor, the patient has to wait a long time. Due to the fact that the cancer may grow and progress, while the man is waiting for their turn, are often held adjunctive therapy (for example, local ablation) aimed at limiting the spread of tumor cells. If the tumor has penetrated beyond the liver for waiting time - further transplantation is undesirable.

Partial liver transplant from a living donor

It performed for the treatment of patients who have been diagnosed with cancer, in those cases when a living person donates a part of his liver to the patient. Reduced during the operation vital organ donor can regenerate and often returns to its original size for several months under the condition that initially he was absolutely healthy. In most cases, the transplanted portion does not provide a complete recovery of liver function. Regeneration and renewal of body normal work of the recipient takes more time than the donor.

The Israeli hospitals often performed a liver transplant from a relative - parent, sibling or adult child. The donor may be a husband or wife.

Who can become a donor for a liver transplant?

People who want to donate their liver, the patient must undergo a full medical examination to ensure that doctors were convinced that the body is healthy, and the operation will be safe for both the donor and the recipient. Also, there are some general limitations of the donor, which must:

  1. Be at least 18 years and in most cases not more than 60.
  2. Quit smoking at least 4-6 weeks before surgery.
  3. To be perfectly healthy, with no serious mental and physical disorders.
  4. Have a compatible blood type of the patient.
  5. Follow all the doctor's instructions before and after surgery.
  6. Have a similar body size.
  7. Being able to go through all kinds of medical tests - blood tests, radiological tests, liver biopsy, etc.
  8. Deciding to donate liver to a patient alone, without any pressure or coercion on the part of interested parties in the transaction.

Before liver transplant surgery in Israel

The patient was diagnosed with liver cancer before surgery is necessary to pass several tests:

  1. Determination of blood group and tissue typing (to make sure that the body does not reject the donor liver).
  2. Blood tests and skin tests.
  3. Heart study - electrocardiogram, echocardiogram or cardiac catheterization.
  4. Checks aimed at confirmation of early stage cancer, as well as to the estimated condition of the liver, blood vessels and surrounding organs - gallbladder, pancreas, small intestine.

If the patient is a good candidate for transplantation, it will wear at a certain place in the waiting list, which depends on the likelihood that the operation is successful, tumor size, general health and other individual factors of the disease. In the case of liver transplantation is conducted from a relative need for long waiting there.

Before a liver transplant patient who waits for a suitable donor organ must:

  1. To follow a special diet.
  2. Do not drink alcoholic beverages.
  3. Do not smoke.
  4. Maintain physical form and to perform certain exercises.
  5. To take all medications prescribed by your doctor and report any changes to their admission and there are any problems.

A full and partial liver transplantation in Israel

When a suitable liver from a deceased donor is obtained, organ transplantation to be performed as soon as possible. After passing a series of diagnostic tests patients preparing for surgery, and doctors carefully check the donor organ.

liver transplant from a relative or a deceased person is a complicated surgical operation and can take up to 12 hours. The patient is under general anesthesia, it also catheter to drain urine, tracheal intubation performed and installed drip for patient necessary medicines and liquid.

At full transplant incision is made in the upper abdomen, and then separates the surgical team diseased liver with blood vessels and the common bile duct, pinches them and removes the liver. Next, doctors attached the donor organ to the same place where it was located a sick liver, the vessels, and ducts. Sometimes around the transplanted organ installed special drainage tubes to drain blood and other fluids from the abdominal cavity. In rare cases, can be used for temporary tube drainage of bile from the liver to the new special bag as surgeons is important to know whether the body produces bile as it should.

As I mentioned above, in Israel practiced in most cases of liver transplantation from a living person. In this case, the operation involved two surgical teams, one of which carries out the removal of the diseased organ recipient, and the second (second operating room) - healthy liver donor site, after which it is transplanted to a patient. Otherwise, surgery and rehabilitation patient differ little from liver transplantation withdrawn postmortem.

Postoperative period and rehabilitation of patients

After surgery, patients are transferred to the ICU. Breathing patients is supported by the unit ventilator, their condition carefully checked for the first signs of infection, and made part of the analysis aimed at assessing the functioning of the new liver. Most recipients spend 1 to 3 days in the ICU, and then redirect them to a subsequent transplant unit, where they start to breathe on their own, but they are still drugs are administered intravenously, and other necessary materials.

Nurses are specially trained to work with patients who have had a liver transplant, helping patients to start eating and walking, is also carried out physical therapy. Every day, patients must take a blood sample, as well as the need to pass X-rays and a liver biopsy, which is performed in cases of suspected rejection of the transplanted organ by the body.

After liver transplantation, and further rehabilitation at the clinic, patients leave the hospital in 10-14 days. For the normal life they come back, usually within 3-6 months after surgery.

Patients who had undergone surgery for a liver transplant, should start to take special medication against organ rejection, and also to carry out regular monitoring of the health status to identify any signs of rejection by the body or liver cancer recurrence.

Medicines to prevent rejection, suppress the immune system, and this, in turn, allows the body to properly perceive the foreign organ. Many patients can be observed at the first signs of liver rejection, but with minimal change those medicines tend to be terminated. Most recipients almost immediately after liver transplantation appointed potent immunosuppressants, because in this period there is the highest risk of organ rejection. Then, within a few weeks or months, the dosage of medicines is reduced.

In most cases, recipients after surgery returned to normal and healthy life, the quality of which is improving markedly. They become physically active, and women are able to conceive after the procedure, carry and give birth to a child.

Complications after liver transplantation:

  1. Recurrence of cancer.
  2. Severe bleeding, difficulty clotting.
  3. Reaction to anesthetic during liver transplantation.
  4. Side effects of immunosuppressive drugs - tremors, hypertension, hallucinations, suicidal thoughts, etc.
  5. The rejection of the liver - the characteristic response of the immune system to a foreign body, usually manifests itself in the first 7-14 days after liver transplantation and is expressed as: body temperature of 38 ºC%, vomiting, diarrhea, yellowed skin and whites of the eyes, pale feces, darkened urine, itching integument.
  6. Infection. Immunosuppressants make the patient the most vulnerable to all kinds of infections (athlete's foot and cytomegalovirus infection).
  7. Leakage of bile.
  8. The development of diabetes (in most cases observed in patients who previously had been ill with hepatitis C).
  9. Renal failure - a serious complication that may occur in 1 in 5 people who have undergone liver transplantation, usually within five years. The primary cause of the disease is receiving immunosuppressants. Symptoms of kidney failure: fatigue, blood in the urine, nausea, shortness of breath, swollen legs, ankles, or hands.
  10. Transplant rejection.

Liver transplant from a living donor has been widely developed in Israeli medical institutions due to restrictions on obtaining organs from dead people. Through this process of transplantation has been refined to a filigree. The use of the most modern medical equipment, the skill of Israeli doctors, complete diagnostic examination of the patient and the donor provides a high percentage of patients recovery and minimal risk of complications.

If you need the best treatment of liver cancer and want to get rid of his illness - please contact our medical service coordination, «Tlv.Hospital» and we will help you choose the most suitable clinic.

Israeli clinic performed the optimal selection of the donor, use of modern surgery techniques, it provides the reliability and safety of the surgical procedure.

life expectancy rate after liver transplant in Israel - is very high, 70% of patients live more than 10 years, and many of 15 and 20 years. It was also observed cases of women with liver transplant successfully gave birth to children.

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