pleural mesotheliomaMesothelioma - a type of cancer that develops in the tissues surrounding the lungs or abdomen. These cells cover the external surface of most of the internal organs, called gasket forming mesothelia.

Advantages of the treatment of mesothelioma in Israel:

  1. Modern methods of treatment, including the use of targeted therapies.
  2. The last, the least invasive surgical procedure.
  3. Advanced methods of radiation therapy, including IMRT - intensity-modulated radiotherapy.
  4. Clinical trials of new methods for the treatment of mesothelioma.

Medical service «Tlv.Hospital» offers the possibility of organizing the diagnosis and treatment of mesothelioma in Israel. Our company - private independent provider with 10 years of experience in the medical tourism market.

We carry selection of the profile clinic, highly qualified doctors, provide full organization of treatment and stay in Israel.

pleural mesothelioma

Approximately ¾ mezeteliom develop in the thoracic cavity - 75%. Malignant pleural process occurs (serous) membranes surrounding the lungs. Pleura performs a protective function, and generates a liquid which facilitates the sliding of the lungs in the pleural cavity when they are stretched and reduced in the breathing process. Mesothelioma, which develops in the pleura is called pleural.

Tissue covering the heart (pericardium), located very close to the pleura. Therefore, some people have pleural mesothelioma spreads to the pericardium.

mesothelioma of the peritoneum

Skin covering the abdominal cavity is called the peritoneum. It protects the organs and keeps them in place. Also synthesizes a lubricating fluid that helps the organs of locomotion.

Mesothelioma tissue lining the peritoneal cavity, known as mesothelioma of the peritoneum, it accounts for 25% of cases. Peritoneal mesothelioma is not usually spread to other parts of the body.

Mesothelioma is a benign nature

Benign tumors can occur in the connective tissue in the lungs or reproductive organs in both men and women. Very rare.

Reasons mezateliomy

This is a fairly rare form of cancer, but is gradually becoming more widespread. It is believed that this is due to exposure to asbestos per person during work activities. Pleural mesothelioma is much more common than mesothelioma of the peritoneum.

Possible risk factors:

  1. It is known that asbestos in most cases becomes a cause of pleural mesothelioma. The risk increases if a person is exposed to it from an early age for a long period of time. It was found that the peritoneal mesothelioma as many people have experienced the impact of asbestos. Asbestos is made of tiny fibers that are in the process of respiration penetrate the pleura, irritate it, causing genetic mutations. The latter leads to an increase in cancer.
  2. SV40 virus known as simian virus, or polyomavirus. People who were exposed to asbestos, some studies have shown that exposure to SV40 virus increases the likelihood of developing mesothelioma. He is considered as a possible risk factor.
  3. Pleural and peritoneal mesothelioma, according to research results may occur due to radiation effect of the chemical substance called thorium dioxide. Some studies suggest an increased risk of developing mesothelioma in people treated with radiation therapy in treating cancer.
  4. Mineral called erionite may cause the development of the disease.
  5. The work of the artist associated with increased likelihood of mesothelioma due to the presence in the ink chemicals.

symptoms of mesothelioma

Mesothelioma Treatment in IsraelIn the early stages of mesothelioma has virtually no symptoms. When symptoms develop, they are often associated with the growth of the tumor process and pressure on a nerve or other organ of the body. The following signs of the disease can also be caused by another disease.

Symptoms of pleural mesothelioma

  1. Chest pain.
  2. Dyspnea.
  3. Fatigue.
  4. Sweating and fever.
  5. Persistent cough.
  6. Wanton weight loss.
  7. Loss of appetite.
  8. Difficulty swallowing.
  9. Hoarse or husky voice.
  10. Changing the shape of the fingers and nails - "syndrome of clubbing" in some people.

Symptoms of peritoneal mesothelioma:

  1. Abdominal pain.
  2. Swelling in the peritoneum.
  3. Nausea.
  4. Poor appetite.
  5. Weight loss for no apparent reason.
  6. Diarrhea or constipation.

The earlier cancer is diagnosed, the easier it is to cure, and the higher the probability of successful treatment.

types of mesothelioma

There are two main types - pleural mesothelioma and peritoneal cavity.

Share mesothelioma cell type:

  1. Epithelioid type - it accounts for 50-60% of cases.
  2. Sarcomatoid - 10%.
  3. Mixed - 30-40%.

Mesothelioma Treatment in Israel

Opting for treatment in Israel, the patient can be sure that his health will be engaged in well-known doctors with a high level of experience and skill. For example,Dr. Ofer Merimsky is a specialist in the treatment of different types of sarcomas, including mesothelioma.

The team, which includes more than 30 professionals - oncologists, surgeons, pulmonologists, pathologists - experts in the treatment of mesothelioma in Israel are working closely together to develop the most optimal therapy program. Specially trained support team is part of this team.

The symptoms of mesothelioma are often similar to the symptoms of other diseases. This may complicate its diagnosis. Early and accurate diagnosis is important for successful treatment of the disease.

If there are symptoms suggestive of mesothelioma, in an Israeli hospital doctor examines a patient, ask questions about health status, lifestyle, including smoking and alcohol consumption, exposure to asbestos. One or more of the following tests may be conducted to determine whether mesothelioma is, and whether the tumor has spread process. These tests can also be performed, that determine how effective treatment:

  1. Fine-needle biopsy of the lungs or fluid drainage.
  2. Pulmonary function tests.
  3. Imaging techniques may include: CT, MRI, PET, X-ray of the thorax.
  4. Thoracoscopic lung biopsy is performed through a small incision in the chest. The doctor inserts a small size thoracoscopy, removes a small amount of tissue, which is further examined under a microscope.

Stage pleural mesothelioma

If confirmed the diagnosis, the doctor will determine the stage of disease. Classifies, establishing how the tumor process spread in the body, and where. It is necessary for the effective planning of treatment of mesothelioma in Israel. Surgery is often required to determine the stage.

Step IA: tumor struck outer pleural layer - parietal.

Step Ib: malignant process has penetrated into the parietal and visceral pleura.

Stage II: Cancer has spread to the lungs or diaphragm (thin muscle that separates the thorax from the abdominal cavity).

Stage III: tumor process involved one of the following areas - pericardium, one of the zones of the chest wall and lymph nodes in the chest.

Stage IV: cancer struck one or more zones, several areas of the chest wall; membrane or pericardium; heart, trachea, esophagus and liver; the opposite lung.

Getting a second opinion in Israel

Diagnosis and Staging of mesothelioma is often a difficult process. You can using the MS «Tlv.Hospital» get a second opinion from qualified Israeli pathologists.

Mesothelioma treatment in Israel, a cancer of the pleura

Treatment of cancer of the pleura in Israelthe country's clinics offer innovative therapies, some of which are only available in a few medical centers in Israel. During treatment, doctors focus on the patient's quality of life and lung function. To this end, specialized procedures apply - less invasive surgical techniques, focused radiation therapy.

Also offered the opportunity to participate in clinical trials, which are available only in Israel. It may be surgery, radiotherapy, chemotherapy or targeted therapy. If surgery is not regarded as an option, it can be recommended treatment targeted agents. Innovative Targeted drugs offer hope for some patients with mesothelioma.

The treatment program will be designed taking into account the following factors: the type of mesothelioma, stage, tumor location, age, and general health.

Surgery

The main objectives of surgical treatment of mesothelioma in Israel:

  1. Reduce the amount of tumor process, to improve the chances of successful treatment with the additional therapy - radiation, chemotherapy, targeted therapy.
  2. Reduce pain and shortness of breath - the symptoms of metastatic cancer.

The two main types of transactions are used for mesothelioma clinics in Israel:

  1. Extrapleural pneumonectomy is considered the best one for surgical treatment in which the tumor is completely removed. This makes it possible to apply other methods of therapy with less risk to other organs.

It is a major surgical procedure involving the removal of organs, which the cancer has spread. This can be the lungs, lymph nodes, segments pericardium and the diaphragm. synthetic materials used for reconstruction of pericardium and the diaphragm. The patient must be in good shape, to bring such an operation.

  1. Plevrektomy or pleurectomy / decortication involves removal of lung tumors, chest wall and diaphragm and preserving the integrity of structures. By this operation, turning, if you can not hold a pneumonectomy due to poor lung or heart function.

Typically, the tumor can not be removed completely. Since the light is preserved and the diaphragm, it is impossible to use high doses of radiation. The risk of recurrence after surgery is significantly higher than after pneumonectomy. A positive aspect is the conservation of lung function.

Radiation therapy

Radiotherapy as monotherapy can not cure mesothelioma. However, when it is carried out after the operation, it may reduce the likelihood of relapse. In the later stages, this method relieves pain and other symptoms.

IMRT is carried out only a few cancer centers in the country. It is used after surgery to remove mesothelioma. Unlike other types of radiation therapy IMRT provides better results and fewer side effects in the treatment of this type of cancer.

Chemotherapy

Israeli hospitals offer the latest mesothelioma chemotherapy protocols. Oncologists who specialize in the field of chemotherapy, have considerable experience. The team of nurses, pharmacists, physicians caring for patients during treatment with cytotoxic drugs, seeking to ensure a good quality of life.

Targeted therapy

Israeli medical centers use the latest drugs for targeted therapy. They are specially designed for genetic / molecular profile of a particular tumor, to help the body fight cancer. Many doctors who treat mesothelioma in Israel, participating in national and international clinical trials of innovative targeted therapies.

Mesothelioma treatment in Israel: the peritoneum

Treatment of basal cell carcinoma of the peritoneum in IsraelDevelopment of this type of treatment program cancer will depend on the stage of the disease, presence of other possible diseases, general health status. Some patients with localized peritoneal mesothelioma may undergo surgery to remove the tumor completely.

Unfortunately, these types of treatment of oncology, chemotherapy and radiotherapy, do not always produce the desired effect with mesothelioma. Doctors and researchers are working in this direction. The patient may be asked to participate in a clinical trial.

Surgery

The operation is not often used in peritoneal mesothelioma, because it requires general good health for such extensive surgery - peritonectomy. It involves removing a portion of the peritoneum (the abdominal cavity mucosa) which expands mesothelioma. The main objective of surgery - to reduce symptoms.

It is also possible holding of cytoreductive surgery. The surgeon performs various procedures to 6, seeking to remove as much of the tumor process. During operation or later introduced into the peritoneal cavity of chemotherapy preheated solution. The application of this methodology physicians have had some promising results.

Chemotherapy

In some cases, mesothelioma intravenously administered cytotoxic (anti-cancer) drugs. Depending on the type of chemotherapy treatment is administered weekly or every two - three weeks, usually on an outpatient basis. The main task - to reduce mesothelioma and keep it under control as long as possible. But for many patients, chemotherapy is ineffective. Research continues, whose main task - to find more efficient methods of carrying out this type of treatment.

For patients with early stage mesothelioma and general good health give chemotherapy directly into the abdominal cavity during cytoreductive surgery or soon after it. The physician makes a small incision in the abdominal wall and enters the catheter through which the solution flows into the cavity. But before it is heated to a temperature several degrees above body temperature. This hyperthermal intraoperative intraperitoneal chemotherapy view. According to the study, half of the people after such treatment have a five-year survival rate, and more.

Supportive care with mesothelioma of the peritoneum

Unfortunately, mesothelioma frequently diagnosed at a late stage when the cancer is metastatic. Some people - too ill to cope with intensive chemotherapy. In such a case, a treatment aimed at alleviating the symptoms - of pain, weight loss, elimination of liquid from the abdominal cavity.

When peritoneal mesothelioma fluid may be collected within the peritoneum. The abdomen becomes convex, it causes discomfort and heaviness. In such case, the liquid "poured" - carried abdominal paracentesis or ascitic fluid evacuation.

The treatment takes a team of palliative care. This is a team of doctors and nurses who are experts in the control of symptoms in the later stages. Also, it may include a physical therapist and a nutritionist.

Prices for the treatment of mesothelioma in Israel

Each case is different diseases, different steps require different therapies. We spend the cost of a number of diagnostic procedures:

  • Consultation oncologist - $ 600.
  • Biopsy - from $ 600.
  • Revision of histology - $ 680.
  • blood tests (general, biochemical) - $ 540.
  • PET-CT - 1670 $.

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