Treatment of colorectal cancer in Israel

Bowel cancer is characterized as a malignant growth of cells at different sites body. Most often Oncology found in the large intestine, but in the small malignant tumors are detected less frequently. Colon cancer is usually diagnosed in patients after forty years. It affects men slightly more often than women. Thanks to the good financing from the state budget, the treatment of colon cancer in Israel has an incredible efficiency. The best clinics in the country are equipped with excellent facilities, they employ highly qualified professionals, and thus the cost of care in the country is lower than in Europe or the US.

If you are considering treatment options for colorectal cancer abroad, an excellent choice would be treated in Israel. Our company «Tlv.Hospital», being an experienced healthcare provider can offer an excellent level of organization diagnosis and treatment from the best doctors at a reasonable cost, taking into account all the individual's wishes.

Learn more about our services and the benefits of choice can be found in a special section. Below are the prices for the program of diagnosis of the disease, at the end of the article - a list of doctors.

colon cancer stage

It is known that colon cancer is capable of hitting a wall or mucosa lining the body shell. Depending on severity of the disease is divided into four major stages of cancer:

  1. Cancer kishechnika1 stage - appearance neoplasm mucosal body.
  2. Colon Cancer Stage 2 - the spread of the tumor to the whole intestine.
  3. Stage 3 colon cancer - nodal involvement.
  4. Bowel Cancer Stage 4 - metastasis, the occurrence of secondary lesions in adjacent organs.

Symptoms of bowel cancer

If you have suspected bowel cancer, its symptoms do not necessarily indicate the presence of cancer in the body. This may be hemorrhoids or other less dangerous disease. Confirm or deny suspicions can only experienced physician after a series of studies. A specialist should apply if in a few weeks there are the following symptoms of the disease:Treatment of colorectal cancer in Israel

  1. Pain in the abdomen.
  2. Blood or pus in the stool.
  3. Violation of defecation.
  4. ileus.
  5. Vomiting, flatulence, and nausea.
  6. Weakness, dizziness.
  7. Aversion to meat diet.
  8. Weight loss.

Also must be periodically tested for the presence of chronically ill citizens of bowel cancer of the body with a genetic predisposition, and those who daily consume fatty foods or meat.

K is an effective cancer treatment in Israel are high professionalism of doctors, access to new developments and their active implementation, the modern medical equipment, excellent diagnostics, individual selection of therapies.

Diagnosis of colorectal cancer in Israeli hospitals

Treatment of colorectal cancer in Israel begins after a thorough examination of the patient. Sophisticated equipment and advanced techniques can accurately identify cancer of the small intestine, or colon cancer. Israeli clinic achieved excellent efficiency, especially if the disease is detected in the early stages. It is also the country's hospitals offer modern techniques for combating the disease, if diagnosed with "intestinal cancer metastasis." Diagnosing a disease can include the following range of inspections:

  • Inspection at the proctologist, palpation.
  • Laboratory stool, urine, blood.
  • US bowel.
  • Computed tomography, visual colonoscopy.
  • MR.
  • Endoscopy.
  • Biopsy.
  • Angiography.
  • X-ray.

On the organization of treatment and diagnosis of cancer in Israel you can contact the medical service en.thebestmedic.com.

Treatment of colorectal cancer in Israel

Quality treatment of cancer in Israelis based on an integrated approach to solving the problem. A combination of different methods allows to achieve excellent performance and cope with the disease forever. The clinic employs highly trained specialists, oncologists, using modern equipment. Colon cancer treatment program in Israel includes the following techniques: chemotherapy, targeted therapy, radiation, surgery.

Treatment of colorectal cancer in Israel - chemotherapytreatment of colorectal cancer in Israel

Chemotherapy uses medication drugs in the fight against malignant cells.

Of the Types chemotherapy for bowel cancer:

  1. Systemic chemotherapy involve administration of drugs intravenously or orally. The drugs enter the bloodstream, spreading throughout the body. This type of treatment is effective at the stage of the disease, when there are secondary foci.
  2. Regional or local chemotherapy involves injecting drugs into an artery leading to the parts of the body, which struck the tumor. It provides a concentrated dose of the drug to the pathological area. This reduces the side effects to a lesser degree exposing the rest of the body. An example is the infusion of the hepatic artery in the treatment of colon cancer in Israel when diagnosed metastases in the liver. It is used less frequently than systemic chemotherapy.

When appointed cytostatic treatment of colon cancer in Israel?

Chemotherapy may apply at different times during the treatment of the disease.

Adjuvant chemotherapy for bowel cancer is administered after surgery to remove the cancer, destroying the remaining abnormal cells which may be unrecognizable even tomography. It helps to prevent relapse. In addition, it has been proven that the second and third stages of cancer of the large intestine and rectum, this treatment increases the life expectancy.

Neoadjuvant chemotherapy, sometimes radiation is carried out prior to surgery in the treatment of colon cancer in Israel, in order to reduce the tumor volume and simplify the operation. It is often performed at the diagnosis - cancer of the colon.

Chemotherapy is assigned in the later stages of the disease as a palliative treatment option to reduce the size of the tumor and alleviate symptoms, in particular at the secondary foci in the liver. Healing is not achieved, but the therapy prolongs life.

Selection methods of treatment of colon cancer in Israel is based on the precision of genetic tests, which reduces unwanted side effects and increases the effectiveness of therapy.

Drugs used in the treatment of cancer in Israel, colon and direct

In the treatment of colorectal cancer is often to improve the treatment efficiency, use a combination of two or more drugs.

the effects of chemotherapy for bowel cancerChemotherapy drugs have a very strong effect, affecting some healthy cells in the body. Treatment is carried out in cycles, where after therapy should be a period of rest, restoring the strength of the body. chemotherapy courses usually last from two to four weeks, and patients usually receive multiple cycles of treatment. The most commonly used drugs in the treatment of colon cancer in Israel:

  • 5-Fluorouracil (5-FU), which is often administered with leucovorin (also called folate), which increases the efficiency of the first drug.
  • Capecitabine (Xeloda ®) in pill form. Once in the body, it is converted to 5-FU when penetrates the tumor.
  • Irinotecan (Camptosar ®).
  • Oxaliplatin (Eloxatin ®).

Common drugs and their combination in the treatment of colon cancer in Israel

Common combinations of drugs used in adjuvant therapy:

  • FOLFOX: 5-fluorouracil, leucovorin, and oxaliplatin.
  • CapeOx: capecitabine and oxaliplatin.
  • 5-fluorouracil and leucovorin.
  • Capecitabine (Capecitabine).

FOLFOX and CapeOx considered stronger, but provoke a greater number of adverse effects of treatment.

Since many embodiments aim used therapies common disease stages:

  • FOLFOX: 5-fluorouracil, leucovorin, and oxaliplatin.
  • FOLFIRI: 5-FU, leucovorin, and irinotecan.
  • FOLFOXIRI (leucovorin, 5-FU, oxaliplatin, and irinotecan).
  • CapeOx: capecitabine and oxaliplatin.
  • 5-FU and leucovorin.
  • Capecitabine.
  • Irinotecan.

Sometimes these drugs give drugs to targeted therapy.

When the treatment of colorectal cancer in Israel, 5-fluorouracil alone or in combination with capecitabine with radiation can assign to the operation.

The negative effects of chemotherapy for bowel cancerthe effects of chemotherapy for bowel cancer

Adverse effects of the treatment will depend on the type, quantity and time of medication. Among the common side effects are: loss of appetite, hair loss, nausea and vomiting, ulcerative lesions of the mouth, low blood counts, increased incidence of infections, bleeding, bruising, fatigue.

At reception of certain drugs can occur specific manifestations. Let us examine them.

  1. Palmoplantar syndrome may be due to capecitabine or 5-FU (using infusion). It manifests itself first as redness of the hands and feet, and later, may increase the sensitivity and the occurrence of pain. If the condition worsens, the skin starts to peel, bubbles appear, which eventually can cause ulcerative lesions. It is important for any early symptoms tell your doctor, as there is the possibility to take measures that will prevent deterioration.
  2. Neuropathy (painful nerve damage) is a common side effect of oxaliplatin. Symptoms include numbness, tingling, or even pain in the hands and feet. Moreover, the appearance of increased sensitivity to hot and cold in the throat and esophagus, which may cause problems in swallowing, eg, pain.
  3. Diarrhea is a common side effect of many drugs of this group, but in particular its appearance associated with the reception of irinotecan. By the treatment of the negative effects begin immediately in order to prevent severe dehydration. Usually take loperamide (Imodium ®).

Most of these adverse effects of chemotherapy in cancer of the intestine is short and disappears on its completion. Some of them, like numbness, for example, may occur a long time. Often there is an opportunity to find ways to reduce these symptoms. For example, there are drugs that prevent or reduce nausea and vomiting. It is important to discuss these issues with the doctors, to report promptly any symptoms. In some cases, there is a need to reduce the number of reception of chemotherapy, stop or postpone therapy to prevent worsening consequences.

Older people are often quite well tolerated by certain types of chemotherapy in colorectal cancer. Therefore, there is no reason to refuse treatment because of their age.

High qualification and professionalism of doctors in Israel is composed of a great education, great experience, the availability of long-term training abroad, continuously improve the level of qualification, employment in scientific activities.

Treatment of colorectal cancer in Israel - targeted therapy

treatment of colon cancer in Israel    When the researchers learned more about the gene changes in cells that cause cancer, they were able to develop new drugs aimed at mutations. These drugs work differently from standard chemotherapy drugs. They also have side effects, but less severe. Targeted therapy may be administered as monotherapy, and in combination with chemotherapy.

VEGF targeted agents in the treatment in Israel, colon cancer and rectal cancer

VEGF is translated from English means vascular endothelial growth factor, it is a protein that promotes the formation of new blood vessels in tumors. Bevacizumab drugs (Avastin ®) and Ziv-Aflibercept (Zaltrap ®), aimed at the factor indicated for the treatment of colon cancer in Israel.

Bevacizumab is a monoclonal antibody. In the later stages of disease are administered in combination with chemotherapy.

Ziv-Aflibercept (Zaltrap ®) is another view of the protein, which can be combined with certain combinations of chemotherapy in stages when the disease throughout the body.

Both drugs are administered intravenously every two - three weeks.

In combination with chemotherapy, these funds Targeted at advanced stages of disease increased life expectancy, but, of course, cause some side effects. Common adverse effects of therapy include high blood pressure, bleeding, fatigue, low white cell count, headache, diarrhea, ulcerative lesions of the mouth, loss of appetite. The rare adverse manifestations include blood clots, excessive bleeding, ulcers in the large intestine, slow healing of wounds, disorders of the heart. Ulcerative intestinal lesion will require surgical treatment.

EGFR targeted therapies in the treatment of Israel colon cancer and rectal cancertreatment of colorectal cancer in Israel

Cetuximab (Erbitux ®) and panitumumab (Vectibix ®) are monoclonal antibodies that attack epidermal growth factor receptor (EGFR) - molecule that often appears in large numbers on the surface of tumor cells and help them grow.

Cetuximab is prescribed after failure of other therapies, when there are metastases in the body. Most often it is taken alone or in combination with irinotecan.

Panitumumab is used to treat metastatic colorectal cancer, usually after the other methods have been attempted therapy.

About four out of ten cases of colorectal cancer have mutations in the KRAS gene that makes them resistant to the action of the above-mentioned drugs. Currently, clinical trials are conducted. It is possible to perform the analysis for the presence of mutations, to find out whether the drug's effectiveness.

Both of these drugs are given intravenously, once per week, or - in two.

The most common side effects are a problem on the skin - a rash on the chest and the face of acne. Admission panitumumab able to aggravate the above identified problems. Other undesirable effects of treatment include headache, fever, fatigue and diarrhea.

A rare but serious side effect of these drugs is an allergic reaction which is capable of causing problems with breathing and low blood pressure. Doctors can prescribe medication before treatment to help prevent these negative phenomena.

Other targeted therapies in the treatment of colon cancer in Israel

Regorafenib (Stivarga ®) is used in the treatment of advanced colorectal cancer. He refers to the form of targeted therapy, known as a kinase inhibitor. Kinases are proteins on the cell surface or near it, important signals transmitting cells control center. Regorafenib blocks the action of certain kinases, which accelerate the growth of tumor cells or contribute to the formation of new blood vessels that feed the malignancy.

According to the results of the research on this drug, it has been found that taking regorafenib increases the life expectancy of about six weeks.

It is taken in pill form. Common manifestations of undesired therapy include loss of appetite, diarrhea, fatigue, loss of body weight, hand-foot syndrome, hypertension, infection, voice changes, ulcerative lesions of the mouth and throat. Among the more serious consequences of receiving note strong bleeding, liver damage, ulcers in the intestine or stomach.

Radiation treatment in Israel, colon cancer and rectal cancer

treatment of colon cancer in IsraelIrradiation is used to destroy cancer cells in colorectal cancer. Chemotherapy may enhance the effects of radiation therapy for certain types of colon cancer. The combination of these two procedures is known as chemoradiation.

Will most the cases with In exposure is Assigned to Patients in the treatment of colon cancer in Israel , the when the disease has the affected the internal Organs or mucosa of the abdominal cavity. In this situation, there is no certainty that all the abnormal cells can be removed by surgery, and radiation therapy is used to destroy the remaining after surgery.

Radiotherapy is also done in the later stages of colon cancer when secondary lesions penetrate into the brain or into the bone tissue.

The treatment of cancer of the rectum in Israel radiation administered before and after surgery, which helps to prevent the return of disease in the primary tumor. Radiotherapy is often performed with chemotherapy.

Many doctors are now advocating for the implementation of radiation therapy in colorectal cancer before surgery to make it easier to remove a malignant tumor, especially if its size or localization difficult surgery. In addition, it reduces the risk of developing tumors in the pelvis. Reduced the number of complications - the formation of scar tissue, problems with defecation.

Irradiation of cancer of the intestine also serve to help control cancer of the colon in patients with contraindications to surgery or to relieve symptoms of the disease in the late stages - pain, bleeding, lock body.

Types of radiation therapy in the treatment of colon cancer in Israel

In the treatment of colorectal cancer using various types of radiation.treatment of colorectal cancer in Israel

  1. External beam therapy is most often prescribed for bowel cancer. Linac directs radiation to the tumor. First, conduct a thorough change to determine the proper doses of radiation and pre pritselivanie.Vneshnyaya radiotherapy for bowel cancer is similar to the X-ray, but the radiation is more intense. The therapy is carried out five days a week for several weeks. Duration may decrease if the treatment is carried out before surgery.
  2. Intracavitary radiation therapy is indicated for the treatment of colorectal cancer in Israel. A small device for a few minutes was placed in the rectum through the anus to provide high intensity radiation. The procedure is repeated about three times at two-week intervals. The advantage of the approach lies in the fact that irradiation does not affect the skin and other tissues, thereby reducing the number of side effects. This may allow some patients, especially the elderly, to avoid major surgery and a colostomy. This type of treatment applied for malignant tumors of small size. Sometimes given as external beam radiotherapy.
  3. Brachytherapy (internal irradiation), in the treatment of colon cancer in Israel is to use radioactive microgranules are placed directly into the tumor. So limited radiation effect on the surrounding healthy tissue. This method in some cases is used in treatment of rectal cancer in Israel, especially if you can not resort to surgery. Typically, the brachytherapy procedure is the only one.
  4. Embolization microspheres with yttrium-90 is carried out with a large number of metastases in the liver and small among them or in the absence of other distant parts of the body. Radiologist introduces a catheter into an artery in the groin and guides it into the hepatic artery. Through a catheter fed radioactive particles coated with yttrium-90. They block some of the small blood vessels that feed tumors, and contribute to the destruction of cancer cells. The latter study showed that this type of therapy can slow the growth of metastases in the liver, relieve a variety of symptoms, increase life expectancy. Contraindications may be some liver disease, previously held body irradiation.

Adverse effects of radiation

It is important to discuss in advance with your doctor the possible side effects of therapy. These may include:

  • skin irritation in the irradiation zone;
  • nausea;
  • irregularities in the rectum: diarrhea, painful bowel movements, blood in the stool, fecal incontinence;
  • malfunction of the bladder: frequent urination, burning and pain during urination, blood in the urine;
  • fatigue;
  • Sexual problems: impotence in men and vaginal irritation in women.

Most side effects will decrease after radiation treatments, but problems such as - irregularities in the rectum and bladder may partially remain. If there are any adverse effects of therapy, it is important to talk to your doctor to reduce or alleviate.

Surgical treatment of colon cancer in Israel

In the initial stages of colorectal cancer surgery is a fundamental way of therapy. Read more details aboutoperations in cancer of colon (Colectomy) and the operations of the rectum (Abdominoperineal extirpation of the rectum).

Prices of treatment of bowel cancer in Israel

treatment plan is assigned a doctor for each patient individually. Complete and accurate cost of treatment will be available only after a survey in Israel. With indicative rates for the procedure can be found in the price list, follow the steps:

Program malignant colon cancer diagnosis:

  1. Receiving specialist - 610 dollars.
  2. blood tests - 550 dollars.
  3. Tests for tumor markers (CEA, CA 19.9) - 240 fraction.
  4. PET-CT - 1660 dollars.
  5. Biopsy (on prescription) - 610 fraction.
  6. Histology of tissues - 670 dollars.
  7. Colonoscopy (on doctor's orders) - 1460 dollars.

Total amount: 3730 (5800) dollars.

A diagnostic program for bowel diseases:

  1. Admission gastroenterologist - 560 dollars.
  2. KLA - 260 dollars.
  3. Blood analysis (biochemical test) - 280 fraction.
  4. Analysis for carcinoembryonic antigen - $ 120.
  5. Analysis CA 19.9 - 120 dollars.
  6. Coagulation - $ 80.
  7. Biopsy - 610 dollars.
  8. Colonoscopy - 1460 dollars.

program Amount: 3490 USD.

Bezoperativnoe treatment:

  1. Targeted therapy - 4700 dollars.
  2. Radiotherapy - 37000 dollars.

radiotherapy:

  1. Receiving expert radiologist - $ 600.
  2. exposure calculation program - 1540 USD.
  3. Radiotherapy - 18,000 dollars.
  4. program Amount: 20140 USD.

Chemotherapy:

  1. One therapy session - 2300 dollars.
  2. Formulations - 360 dollars.

Resection of the tumor:

  1. US - 480 dollars.
  2. Consumables - 4000 dollars.
  3. Surgery - 24000 dollars.

Total: 28480 USD.

After surgery, the patient is in the clinic (cost of stay is included in the price of surgery). To prevent the development of relapse is possible to assign radiation or cytotoxic drugs.

Coordination Center en.thebestmedic.com become your trusted advisor and a conductor from the beginning of the diagnosis at Israeli hospitals to full recovery and return to their homeland.

Consultations with video online a leading Israeli experts: about the benefits of online video Consultation.