bone cancer in IsraelBone cancer - an umbrella term, which is called malignant tumors of bone tissues. Bone tumors are extremely rare. They constitute about 1% of the total number of malignant cancers. In medicine, it decided to allocate two types of bone cancer:

  1. Primary bone cancer - arises from the uncontrolled division of abnormal bone cells. It is more common in young age.
  2. Secondary bone cancer - is the result of metastasis other body afflicted with cancer.

The treatment of such complex diseases as bone cancer, it is important to entrust a highly professional doctors. Our company - the medical service en.thebestmedic.com help solve the selection of the medical center and specialists problem.

We are professionally engaged in the organization of treatment in Israel for over 10 years, working on a contract basis with 7 hospitals in the state. We in good faith approach to their duties and be able to provide the impeccable organization of diagnosis and treatment in Israel.

Bone cancer is a very dangerous disease, which could result in limb amputation. Therefore, scientists are continually research in this area. To date, the treatment of bone cancer in Israel is considered one of the best in the world. Israel Clinic are developing a very effective treatment program, depending on the variety of bone cancer (chordoma, chondrosarcoma, osteosarcoma, giant cell osteoblastoma, Ewing's sarcoma, fibrosarcoma, etc.).

As with other types of cancer, the exact causes of bone cancer, scientists still can not determine. But it was possible to allocate the categories of people who are most vulnerable to the emergence of bone cancer:

  • Hereditary predisposition.
  • Genetic disorders (Fraumena syndrome).
  • The presence of an umbilical hernia at birth.
  • Paget's disease.
  • The impact of radiation on the body.
  • Age 20 years and older than 65 years.
  • bone injury.

Citizens who are at risk should take into account that if the developing bone cancer symptoms in the body begin to appear, most likely in the late stages. such symptoms can be attributed to the symptoms of bone tumors:

  • Bone pain, worse with time.
  • Swelling in the affected area of ​​bone.
  • Brittle bones, frequent fractures.
  • Fatigue, lethargy.
  • Sweating, fever, chills.
  • Labored breathing.

If any of the symptoms observed in the patient for a few weeks, and at the same time increases symptoms, be sure to consult a specialist. To confirm the diagnosis requires a special diagnostics on professional equipment. Top Israeli clinics are perfectly equipped for this purpose.

Diagnosis of bone cancer in Israel

bone cancer treatment in Israel begins with the quality of diagnosis of the tumor. Israel's hospitals are well equipped with the most modern research equipment. Also used a number of innovative techniques developed by the world's best specialists. Comprehensive survey include:

  • Consultation with a specialist oncologist.
  • Laboratory research.
  • MRI (one of the best methods of diagnosis of cancer of bones).
  • PET-CT (detection of metastases).
  • Bone scan (spread of cancer diagnosed in the other bones).
  • A biopsy (surgical or needle).

Modern diagnostics allows very accurately determine the type and location of cancer localization. Therefore, the treatment of cancer in Israel is very effective. en.thebestmedic.com Coordination Center will be your reliable partner in the organization of treatment of bone cancer in Israel.

Treatment of bone cancer in IsraelTreatment of bone cancer in Israel

bone cancer in Israel is treated differently, depending on many factors. Guide type of cancer, size and location of the tumor localization, the presence of metastases, as well as the age and certain physiological vital signs. Most often, the doctor prescribes a comprehensive treatment of cancer patients. It uses a combination of the following therapeutic modalities:

  • Surgery .
  • Radiation therapy.
  • Chemotherapy.
  • Palliative treatment.

Most often for the treatment of bone cancer surgery is used in Israel. The surgery involves removal of the affected tissue cancer. The operation is performed under the constant supervision of an ultra-modern equipment. So unable to cause minimum damage to healthy tissue. In some severe cases require amputation of a limb or part thereof. It should be noted that the efforts of high quality physicians, combined with the most modern methods of treatment in 90% of cases you can save bodies with their full functionality. If necessary, use bone grafts.

In 90% of cases of bone cancer, Israeli doctors use ablative techniques that save the limb and life.

Chemotherapy in the treatment of bone cancer in Israel

Chemotherapy in cancer treatment uses cytotoxic drugs. This method is very effective for certain types of malignant bone tumors, in particular for Ewing's sarcoma. Israeli doctors often prescribe chemotherapy for osteosarcoma and Kaposi's spindle. Also, this method is combined with surgery or radiotherapy. Chemotherapy for bone cancer is carried out:

  • Before surgery to reduce the tumor volume.
  • After surgery to reduce the likelihood of a return of the disease.
  • With radiotherapy with unresectable Ewing's sarcoma.
  • In order to reduce or control the symptoms of advanced cancer.
  • In order to slow down the process of metastasis.

How is chemotherapy for bone cancer?

Treatment usually consists of several procedures. Appointed reception cytostatic agents for several days, then followed by a break for a couple of weeks - all this is one cycle. The program includes several chemotherapy cycles, the minimum - six. When Ewing's sarcoma is assigned to 14 cycles.

As the treatment is carried out in Israel bone cancer depends on the specific drug or combination thereof: using a dropper, a central catheter or PICC line system. The latter two options are used, usually with an intensive course of chemotherapy. Central catheter is recommended, if some chemotherapy drugs can damage the small blood vessels.

Chemotherapy for bone cancer before surgery in Israel

Many people with this diagnosis of chemotherapy administered both before and after surgery. Preoperative treatment helps shrink the tumor, the surgeon can easily remove it. This makes it possible to carry out organ-sparing surgery or instead of amputation.

Chemotherapy after surgery

In any form of cancer the risk of relapse, even in the complete removal of the tumor. Treatment of bone cancer in Israel cytostatic agents is carried out to reduce this probability. Chemotherapy significantly improves the cure rate for primary bone cancer.

cytostatic treatment is prescribed, even if you can not completely remove the tumor. With chemotherapy, attempts to decrease it. For such situations, even if the tumor is reduced, there is a high risk of the disease returning in the future.

Chemotherapy to relieve symptoms

This kind of treatment of bone cancer in Israel is called palliative. When an inoperable tumor chemotherapy is performed to reduce the tumor process, slow down its development, alleviate the existing symptoms of the disease.

The effectiveness of surgical treatment due to factors such as the surgeon's experience and skills, accurate diagnostic results. Therefore, it is important to choose a medical institution.

Chemotherapy for cancer of bones in Israel

Many different drugs may be used for treating bone cancer usually applied combination. A doctor in the Israeli clinic provides written information about medicines prescribed. Plans called chemotherapy schemes. Mode includes the names of specific drugs and dosages. How should I take drugs, it is determined based on the results of clinical trials.

Chemotherapy for Ewing's sarcoma

When Ewing's sarcoma most commonly used scheme VIDE, which includes the following medications:

  • vincristine
  • ifosfamide
  • doxorubicin (adriamycin)
  • etoposide

The cycle takes three weeks, the entire course - 18 weeks. Often, after this operation carried out therapy or radiation therapy, or a combination thereof. It can then be continued chemotherapy - used other VIA or VAC circuit.

VIA

  • vincristine
  • ifosfamide
  • actinomycin D

VAC:

  • vincristine
  • actinomycin D
  • cyclophosphamide

Both schemes - VIA and VAC is carried out for 3 weeks, this treatment of bone cancer in Israel comprises 8 cycles. If the assigned radiation therapy after surgery, it is usually combined with VIA or VAC.

In some cases, your doctor may recommend an experimental, more intensive treatment is in clinical trials for Ewing's sarcoma. This so-called high-dose chemotherapy, which is held in conjunction with stem cell transplantation. This method doctor may suggest, if it believes that there is a high risk of relapse. Prior chemotherapy was collected by doctors in a patient and retain the stem cells, after - their return into the organism to restore bone marrow after high dose of cytotoxic drugs.

Chemotherapy in osteosarcoma

Apply different combinations of drugs with osteosarcoma. The cycle takes 5 weeks. The first and second day administered cisplatin and doxorubicin. This is followed by a break. At the beginning of the third and fourth weeks given high-dose methotrexate. In order to control side effects intravenously administered another drug - folic acid for 2-3 days after methotrexate.

The patient during this treatment of bone cancer in Israel is in the hospital. He recommended to drink plenty of fluids to the body came cisplatin. patient also delivers blood tests.

Chemotherapy for sarcoma Spindle

Spindle sarcoma includes fibrosarcoma and malignant fibrous histiocytoma. Chemotherapy for this type of bone cancer is similar to the treatment of osteosarcoma, but the dose can be reduced for the elderly.

Chemotherapy at relapse

If osteosarcoma returns after initial treatment, these drugs can be recommended:

  • ifosfamide and etoposide
  • docetaxel and gemcitabine

At relapse of Ewing's sarcoma is used:

  • ifosfamide
  • carboplatin, and etoposide
  • irinotecan and temozolomide.
  • cyclophosphamide and topotecan.

Common side effects

All cytotoxic drugs have side effects. Their development is due to the following factors:

  • what drugs were used;
  • how much medication was prescribed;
  • individual response.

Sometimes undesirable effects occur very little, and sometimes - a lot.

Common side effects include:

  • Reducing the number of blood cells, which causes an increased risk of infection, anemia, and bleeding.
  • Diarrhea.
  • Fatigue.
  • Inflammation in the mouth.
  • Thinning or hair loss.
  • Loss of appetite.
  • Skin rashes.

The doctor will help with any emerging side effects.

Cisplatin and ifosofamid can cause problems such as numbness and tingling. Almost always improve after the end of treatment. Necessarily need to be made aware vrvacha, as the dose may need to be adjusted. Cisplatin also can affect the kidneys, doxorubicin - at heart. Therefore prior to treatment are assigned additional tests - blood tests, an electrocardiogram, an echocardiogram. This diagnosis may be required during and after chemotherapy for bone cancer.

Some chemotherapy drugs can cause infertility. Therefore, in the treatment of children and young people, doctors use drugs, do not provoke problems with fertility. There is also the possibility of freezing sperm, eggs to increase the chances of having children in the future.

Israeli doctors have successfully carried out reconstructive surgery after sparing surgery for maximum recovery functions limb.

Radiation therapy of primary bone cancer in Israel

Often used in this disease IMRT - intensity modulated radiotherapy. It forms the radiation closely matches the shape of the tumor.

Radiation therapy in the treatment of bone cancer in Israel is carried out in the following cases:

  • If the tumor can not be removed because of its location.
  • In Ewing's sarcoma before surgery.
  • To reduce the risk of recurrence after surgery or chemotherapy.
  • If bone cancer does not respond to treatment with cytostatics.

When the tumor occurs in the central part of the body, there is no way to remove it completely, the combination of surgery and radiation therapy, or just radiation therapy may be recommended. In Ewing's sarcoma carried chemoradiotherapy.

Acronym tumors by irradiation to facilitate its removal operations. It will need a smaller volume surgery.

If doctors believe that cancer cells may be left behind after surgery, radiation therapy will be recommended to destroy them. When Ewing's sarcoma that has metastasized to the lungs, lung radiation therapy after chemotherapy. The patient receives a low dose daily for several weeks.

If the cancer has spread or come back after treatment, it can not be cured. However it is possible to control the progression of the disease for a certain time with radiation therapy and chemotherapy.

Palliative radiotherapy is performed:

  1. When secondary outbreaks of disease.
  2. To monitor the development of metastatic disease.
  3. In order to alleviate the symptoms of bone cancer.

Growing tumor can cause symptoms, exerting pressure on the nerves and other tissue. Radiation therapy often reduces them, makes it easier to pressure, strengthens bones.

When and where radiation therapy for bone cancer?

irradiation procedure is performed in specialized departments of radiotherapy in Israeli hospitals. The patient can not give all of the radiation dose at a time, as this will cause too many side effects and damage to normal tissue. Therefore, the irradiation dose or divided into fractions. This treatment of bone cancer in Israel is performed daily, weekdays.

Most often, radiation treatment is administered once a day for several days or weeks. When Ewing's sarcoma patient is given a course of chemoradiotherapy, when the irradiation procedure is carried out twice a day for the first two weeks. This so-called giperfraktsionnaya radiotherapy. Followed by a week of rest, again after radiotherapy - 7 days following chemotherapy cycle.

Radiation therapy is measured in gray (Gy). For example, daily fraction of 2 g for 30 procedures will give the total dose - 60 Gy.

Careful planning is performed before the radiation treatment of bone cancer in Israel. Calculated dose determined place, which will be subjected to therapy. Carried CT, MRI or PET, to identify tumor and adjacent structures disposed. treatment zone marked with special tags.

If the exposure will get an arm or leg may need special forms, which provide the immobility during treatment.

The procedure itself radiotherapy can last from one to several minutes, without causing any pain. It is important to keep the maximum immobility.

Potential side effects

Radiotherapy can cause unwanted effects, including note:

  • fatigue;
  • reddening of the skin in the treatment zone;
  • Hair loss in the treatment area.

Radiotherapy causes fatigue in many people. Other side effects depend on what part of the body is subjected to irradiation. For example, a patient may experience nausea, lose your appetite if the treatment area is located next to the stomach.

Rehabilitation after treatment of bone cancer in Israel

Rehabilitation - an important part of the return to everyday life after treatment. The recovery process for each person is unique, it is due to the degree of the disease, the methods of treatment and many other factors. The patient can be confusing for the following possible problems:

  1. Muscle weakness.
  2. Problems in carrying out daily activities.
  3. Difficulties in managing the upper or lower extremities.

physical rehabilitation

This treatment, during which special exercise, massage, physical therapy to restore health after treatment of bone cancer. the rehabilitation therapy to specialist meets with the patient to explain the treatment.

Rehabilitation after surgery

After sparing surgery recovery process is more complicated than after amputation.

  1. After amputation, the patient learns to use a prosthesis. As a rule, most people start to walk with high-quality physical therapy in 3-6 months.
  2. After sparing surgery the patient starts walking after a year. Without rehabilitation of limb salvage can remain useless.

After surgery, the patient taught special exercises that help maintain muscles strong and joints moving. Sometimes you need a cane, crutches or a walker to help start walking.

Rehabilitation after radiation therapy

in limb Radiation therapy can lead to joint stiffness, reduced movement and loss of muscle strength. Physiotherapy helps to prevent or minimize disability after irradiation.

The cost of diagnosis and therapy

Treatment of bone cancer in Israel always consists of several stages. For accurate diagnosis, each patient is undergoing tests. Brought documents on past research also studied (taking MRI scans, CT scans, PET must be good), but to develop a treatment plan for the passage of diagnostic procedures and specimen collection are required. The program of the survey include:

  1. Consultation with a specialist in oncology - $ 600.
  2. A blood test (biochemical) - $ 270.
  3. KLA - $ 260
  4. The test for tumor markers - $ 120.
  5. Osteostintsigrafiya - $ 710
  6. Revision material (pathology) - $ 680
  7. PET-CT - 1680 $

Total: $ 4,320

Your doctor may prescribe other treatments. For example, radioisotope bone scan - 710 dollars.

Treatment of bone cancer is conducted by various methods, or combinations thereof depending on the stage of tumor development, its features, the body of the patient and other factors. We provide indicative prices for the following procedures:

  1. Isolated limb perfusion - 28 000 $.
  2. Chemotherapy - from 1 180 $ per session, cytotoxic drugs - from $ 360.
  3. Radiation therapy for the field - from $ 140.
  4. Immunotherapy - 2300 $.
  5. Tumor resection - 26 000 $.
  6. Amputation - 27 00 $.

The cost of surgical treatment already includes the necessary materials, payment of specialists, and hospital stay. Depending on the results of treatment physicians may assign repeated assays and procedures to assess the patient's condition.

More detailed information on prices can be obtained after the treatment in our medical service with your phone, the request form, or e-mail.

Online video consultations with leading Israeli experts: about the benefits of online video consultation.