Tlv.Hospital company offers prostate cancer treatment in Israel in leading clinical institutions of the country, have the best doctors, using modern technologies, with the latest technical equipment, medicinal formulas of last generation.

Precision diagnostic systems, professional doctors, intelligently created therapeutic programs based on traditional techniques and copyright - allow effective treatment of prostate cancer.

If the disease is detected in its early stages, the success rate of corrective procedures as high as 98%.prostate cancer treatment in Israel

However, patients in the later stages is a complete restoration of health services, improve health, quality and length of life. Israel is often taken for those clinical cases in which the Russian-speaking countries refuse to work, helping heavy patients get rid of pain, fear, recover and regain confidence in the future.

Clinics, where treatment of prostate cancer in Israel:

  1. Assuta (Assuta) - the premium segment of private medicine, a leading medical institution in the Middle East, where world-class experts work. Haim Matskina - oncologist with experience of over 30 years (member of scientific research in the MP oncourology Miami and Memphis), Svetlana Zalmanova -. The head of the Institute of radiation therapy clinics, etc. They conduct robotic surgery, preserving full erectile function in 80% of cases.
  2. Ichilov (Sourasky) - State Hospital, known all over the world with innovative designs and impeccable practice of treating patients. Laparoscopic surgery using the robotic system da Vinci here holds Gershbaum doctor, one of the best oncourology New York and Israel.
  3. Hospital Chaim Sheba - a hospital with good technical equipment, professional personnel, a strong science base and research in the treatment of prostate cancer. It uses a full range of robotic medicine. The Center is headed by Professor Berger, having an international name in the field of oncological urology and radiation therapy.
  4. Asaf ha-Rofe - part of the public health system, the recognized leader in the field of cancer pathology correction.
  5. Rabin Center (Oncocenter David) - the largest hospital, serving up to 20% of cancer patients in Israel.
  6. Herzliya Medical Center - a private hospital complex, which uses copyrights and classical methods of cancer treatment.

Consult with our experts, which undergo treatment for prostate cancer in Israel, to provide proof of earlier diagnosis used line therapy.

Leading specialists of the Israeli treatment of prostate cancerTreatment of prostate cancer rates in Israel

In Israel, working lights medicine, treatment for which ensures optimal protocol pathology correction. Among them:

  1. Professor Alexander Greenstein - combines management of private practice in Assuta hospital work in Ichilov Hospital, where he is a leading expert prostate cancer pathologies. He graduated from the Hebrew University, trained in the United States (Virginia). Conducting surgery on the TURP procedure, teaches at the University of Tel Aviv, preparing a decent frame rates for the Israeli medicine. Has been active in research, is published in international scientific journals.
  2. Professor Haim Matskina - a recognized expert in the field of oncological surgery urological profile. Practiced for performing complex surgical procedures using modern equipment, technical systems. He graduated from the Hebrew University, residency held at the Tel Aviv Medical Institute. He conducted research in America. Printed in scientific journals. Is a specialist high level of skill on the treatment of prostate cancer in Israel, operates and abroad - at the invitation of the world's leading clinics.
  3. Dr. Alex Tsivyan - practicing techniques laparoscopic surgery for the correction of prostate cancer lesions. Reconstructs damaged organs in Assuta hospital, where he heads the profile department. He graduated from the University of Medicine in Leningrad, trained and receive additional training in Portugal, France, America, Germany and Italy.
  4. Dr. Svetlana Zalmanova - leading radiologist Israel, headed the department of radiation treatment in Assuta. Basic education received in Moscow, total work experience of over 35 years. She trained in the UK, Germany and Denmark. An expert in the field of targeted therapy, radiation biology, and other related industries. He teaches at Ben-Gurion University, conducts active research work.

Among other specialists are often marked by the names of Dr. Eliyahu Gez, Ra'anana Berger, Professor Moshe Inbar.

Rates of prostate cancer treatment in Israel - how to save

Treatment of prostate cancer rates in IsraelPrices for diagnostic and therapeutic procedures are significantly different in different medical centers in Israel. If you want to save money, to contact an experienced medical providers who know how much this or that service in the hospitals of the country. Working directly with 7 clinics in Israel, we will help to optimize the patient's budget, choosing where to spend an expensive procedure.

We organize the healing process in the shortest possible time, including weekends and holidays, saving money addressed to us a person to stay in a foreign country. We help to purchase pharmaceuticals in Israel pharmacies with the smallest margin by employing firm offer.

Also, in general, as a private independent provider of our company we offer low prices for logistics services, compared to the prices in the international organization of treatment clinics departments.

The following are the approximate prices of diagnostic and therapeutic programs.

Diagnostics:

  • Consultation of the oncologist - $ 600.
  • Full blood count - $ 260.
  • Analysis of tumor markers - $ 120.
  • Biochemical analysis of blood - 280 $.
  • Revision of pathology - $ 680.
  • US - $ 440.
  • PET-CT - 1670 $.
  • CT - 670 $.
  • Radionuclide bone scan - $ 710.

Treatment:

  • Cryotherapy tumor - $ 9000.
  • Chemotherapy - $ 1440.
  • Brachytherapy - from $ 18,000.
  • Operation using the Da Vinci robot - from $ 20,000.
  • Laparoscopic Prostatectomy - from 18 to $ 400.
  • Tookad - from 14 100 $.
  • Radiation therapy for the field - from $ 160.

The cost of an individual program of treatment depends on many factors - the diagnostic results, presence or absence of an earlier therapy, the patient's health, etc. To get more detailed information, please use the request form ..

Prostate cancer

Prostate - iron size of a walnut, a place of production and storage of sperm, milky liquid supplying sperm. prostate diseases have a negative effect on the bladder and sexual function. The most common prostate cancer is common in men older than 50 years. More than 90% of cases detected until the change did not go beyond the limits of the body. Distributed anomaly in the absence of therapy by differences cancer cells beyond the prostate capsule or seminal vesicles. Sometimes pathology affects the lymph vessels pelvis, bone structure.

Diagnostics

One of the first steps to determine the prostate cancer is a digital rectal examination (DRE) and a blood test PSA prostate-specific antigen (PSA). Carrying out regular tests increases the chance to detect a tumor at an early stage. Abnormally high PSA is not 100% for the presence of cancer in the body changes. The risk of disease increases with the growth of PSA:

  • 8% probability in PSA of less than or equal to 1.0 ng / ml;
  • 25% with a PSA level of 4-10 ng / ml;
  • 50% in figures above 10 ng / ml.

At high levels of PSA may also be affected by factors such as a prostate infection, benign prostatic hyperplasia, recent sexual activity. If you find a high PSA, it recommended additional screening assessment of a patient. This can be ultrasound, biopsy. It must be remembered that the primary biopsy can give a false negative diagnosis, so the method is applied to several times. The recommended age for routine annual screening of men's health is 40-50 years of age and older.

If there are metastatic lesions is possible to assign the following tests:

  • CT;
  • MRI;
  • bone scan;
  • lymph node biopsy.

On the first visit to the Israeli clinic for diagnosis and treatment of the patient is under scrutiny highly professional team of experts who will personalize every aspect of health care in accordance with the particular case of the disease. This greatly increases the chances of successful treatment and recovery. Apply the latest technologies and techniques with the least adverse effect on the body.

Prostate Cancer Treatment in Israel

Treatment in Israel Cancer, Effectively AT all stages directory. Malignant prostate tumor treated by various methods:

  • watchful waiting or active surveillance;
  • surgery;
  • exposure;
  • cryosurgery;
  • hormone replacement therapy ;
  • chemotherapy;
  • vaccine treatment;
  • treatment of bone metastases.

These methods are appointed, usually individually, but in some cases they can be combined.

In the development of treatment programs take into account such factors as:

  • age and life expectancy;
  • the presence of any other serious illnesses;
  • stage cancer;
  • patient and physician views on the methods and possible side effects.

It is useful to get a second opinion about the best treatment options, depending on the specific situation, identify achievable goals and potential adverse events.

With patient work urologist, radiation oncologist (irradiation); oncologists carrying medication for prostate cancer in Israel (chemotherapy, hormonal therapy); nurses, nutritionists and others.

Watchful waiting and active surveillance treatment of cancer of the prostate in Israel

If this low-risk disease, a number of men may not need treatment. Terms watchful waiting and active surveillance, some experts believe synonymous, while others are treated differently.

Active surveillance involves the monitoring of the disease, the level of prostate-specific antigen, conducting a digital rectal examination, ultrasound at intervals of three to six months to see, does not develop, whether the disease. Transrectal biopsy is appointed, if the cancer becomes aggressive character can spend 1 time per year. Deterioration in the diagnostic results raise the question of the treatment options for prostate cancer in Israel.

Expectant management involves less intense type of surveillance, fewer tests and studies to a greater extent of disease symptoms.

Active surveillance helps to avoid the side effects of treatment. Besides that, doctors do not believe that this method will help to prolong life. Certain risks and side effects may outweigh the potential benefits. With this method of therapy there is a chance that the cells spread in the body. This will limit treatment options and reduce the chance of cure disease.

Watchful waiting is recommended when there are no symptoms, and the tumor grows slowly (Gleason score), it has a small size and localized within the gland.

There are debates about the effectiveness of the active and passive therapy. To date, no radominizirovannyh studies comparing the effectiveness of active surveillance with surgery and radiation therapy.

Chemotherapy for prostate cancer prolongs life, slow the growth of malignant cells, reduces symptoms and improves quality of life.

Chemotherapy for prostate cancer

Chemotherapy was conducted by intravenous administration or oral administration. It is used mostly for metastatic cancer. This method is used in the propagation of abnormal cells in the tissue near the prostate, and when the hormone has no efficient effect.

Chemotherapy given cycle (for several weeks), alternating with periods of rest for recovery.

In prostate cancer, chemotherapy is not indicated in the complex:

  • Docetaxel (Taxotere ®)
  • Cabazitaxel (Jevtana ®)
  • Mitoxatrone (Novantrone ®)
  • Estramustine (Emcyt ®)
  • Doxorubicin (Adriamycin ®)
  • Etoposide (VP-16)
  • Vinblastine (Velban ®)
  • Paclitaxel (Taxol ®)
  • Carboplatin (Paraplatin ®)
  • Vinorelbine (Navelbine ®)

As a rule, the first prescribed docetaxel with prednisone. If the effect of - no, cabazitaxel used - a new drug.

Side effects of chemotherapy

This type of therapy has a damaging effect not only on tumor cells, but also on healthy segments: mucous membranes, hair and bone marrow.

Side effects depend on the time of taking the drugs, their type and amount:

  • feeling tired due to the low content of red blood cells;
  • bleeding and bruising;
  • increased risk of infections due to deficiency of white blood cells;
  • diarrhea;
  • vomiting and nausea;
  • loss of appetite;
  • oral ulcers;
  • hair loss.

The bulk of these manifestations are short term. Also used drugs that prevent them from occurring or reduce.

Surgery for prostate cancer

Surgery is one of the main types of treatment for this disease. On the methods of surgical treatment of the disease can be found in detail in the following articles:

  1. Radical prostatectomy in Israel
  2. Laparoscopic prostatectomy in Israel

Israeli doctors actively using a minimally invasive approach in the surgical treatment successfully conduct nerve-sparing surgery, preventing erectile dysfunction (its probability is then 3%). Extremely important is the experience and professionalism of the surgeon.

Innovation in the treatment of prostate cancer in Israel

Sipuleucel-T (Provenge®) - is an immunotherapeutic drug, vaccine.

Apply this type of treatment if disease has last stage, asymptomatic or does not respond to hormone therapy.

The vaccine is made individually. Leukocytes are removed from the blood with a special drug. In the laboratory, they are subjected to the effects of the protein of malignant prostate cells. Then the leukocytes are administered back to the patient. Entire procedure is performed three times in three weeks.

The application of this vaccine as a whole helps to increase the patient's life for a few months.

Side effects better tolerated than after hormonal therapy or chemotherapy. Note headache, fever, pain in the joints and back pain, nausea, chills during the first two days after the infusion. Rarely observed high blood pressure, respiratory disorders that disappear after treatment.

Cryosurgery for Prostate Cancer

Cryosurgery (also called cryotherapy or cryodestruction) in many cases prescribed for the treatment of early stages of cancer by freezing.

The procedure is as follows. Used epidural or general anesthesia. With the prostate transrectal ultrasonography administered hollow probes through them fed nitrogen or argon, they destroy the prostate. In the absence of damage to the surrounding tissue carefully observing physician by transrectal ultrasonography. To prevent freezing of the bladder into the urethra catheter is inserted, through which it enters the warm sea water. The catheter remains in the body for a further 3 weeks. You may need to stay overnight in the hospital.

Cryosurgery is less invasive than radical prostatectomy: less blood loss and pain, shorter hospitalization and full recovery.

Compared with surgery and radiation, there is much less information about the long-term effectiveness of cryosurgery. In recent years, there are many available methods, which are used during the ultrasound monitoring of temperature.

For this reason, most of the experts are not often prescribed cryosurgery as a primary method of treatment of prostate cancer. And sometimes recommended for relapse.

Possible side effects of cryosurgery

Adverse symptoms worse treatment if the patient has previously held radiation.

The following symptoms point:

  1. Blood in the urine for one or two days after the procedure, pain in the probe placement.
  2. Swollen state of the scrotum, or penis.
  3. Pain, burning because of the effects of freezing. Frequent urge to empty the bowel and bladder. To restore the normal operation of the authorities is required for a long time.
  4. Erectile dysfunction in four of the five men in connection with damage to the nerves near the prostate. A significantly higher percentage, compared with prostatectomy.
  5. Urinary incontinence especially in those who have previously held radiation.
  6. One percent of men there is a fistula (abnormal connection) of the rectum and bladder. further operation is required.

Israel Hospitals use advanced prostate cancer therapies, including the use of a vaccine (Provenge®), gene therapy and proton.

Radiation therapy to treat cancer of the prostate in Israel

Irradiation is prescribed in the following cases:

  1. As initial treatment, if the low-risk disease, when the tumor is localized clearly.
  2. In the first procedure, along with hormone therapy in secondary malignant lesions in the Surrounding tissues.
  3. After surgery, if there had been no complete removal or were recurrences.
  4. In the later stages of the disease to reduce the volume of malignancy and facilitate existing and future manifestations.

Two types of radiation: external radiotherapy and brachytherapy.

External-beam radiation therapy

This type of radiation therapy administered in the initial stages of the disease, or in the late - to relieve pain in the bones, which causes malignant lesions arising from them.

First performed diagnostic procedures such as MRI, CT. Correctly calculated radiation dose and location.Treatment in Israel is carried out five days a week for seven to nine weeks on an outpatient basis.

3D-conformal radiation therapy for prostate cancer

This method of exposure is almost entirely irradiated volume closer to the shape of the tumor. It carried out full coverage of malignancy. In addition, minimizing damage to healthy tissue around the abnormal area. Therefore, says fewer complications.

IMRT

Treatment of prostate cancer rates in IsraelThis is an advanced method of high-precision irradiation held in Israeli hospitals. Computerized linear accelerators deliver correctly calculated radiation dose to cancer hearth, or to a segment within it. The CT scan can see the shape, size and intensity of the tumor. beam of radiation is divided into bundles, each bundle is controlled. This method is frequently used for prostate cancer.

IGRT technique is used, which in real time detects the amount and localization of tumors, the movement of which, for example, carried out in the breathing cycle, on the whole respectively natural movements of the human body.

A variety of IMRT is RapidArc technology, which is a combination IGRT and IMRT. Irradiation monitored visually modulate its intensity while changing the shape of the beam, the rotation speed of the accelerator, if necessary. This technology is more accurate, variability, provides rapid treatment of prostate cancer in Israel.

The method involves placing small implants in the prostate, which will help determine the exact place of the irradiation field. It helps compensate for the movement (as in breathing), and reduces radiation. Accelerators are applying this technology, known as "Calypso» (Calypso®).

SBRT

This method delivers more radiation doses to a specific area in need of treatment. Treatment period of a few days. SBRT is known as Gamma Knife, CyberKnife. Side adverse events are the same, and in some cases worse, than with IMRT.

Innovation - proton beam therapy for prostate cancer

Instead of X-rays used proton beams. In contrast, proton beams operate within the tumor without damaging adjacent organs and tissue. Accordingly longer delivered to the prostate irradiation and applied less damage to healthy tissues. However, studies have not shown a great effectiveness in the long term. This therapy is not widely available due to the very high cost of the equipment.

Side effects of external radiation

The above-described new methods of treating prostate cancer in Israel provide a smaller number of potential adverse events:

  1. Bowel problems: perhaps the development of the so-called radiation proctitis. He may be accompanied by diarrhea, sometimes bloody diarrhea. For a long time most of the manifestations of the leaves, rarely intestines work does not come back to normal.
  2. Bladder problems: exposure can lead to inflammation of the bladder and the development of radiation cystitis. Symptoms: frequent urination, burning during urination and / or blood in the urine. In most cases, the disorder are, but about 1 in 3 patients can stay.
  3. Urinary incontinence is less common than after surgery.
  4. Erection problems, including erectile dysfunction. The risk of data breaches grows slowly over a year or more, immediately after treatment emergent adverse events was observed. The older the patient, the higher their risk.
  5. Feeling tired, which can pass only a few months after stopping treatment.
  6. Lymphedema: when irradiated lymph nodes, possible accumulation of fluid - the development of edema in the legs or genitals.
  7. Urethral stricture: after therapy is likely scarring and narrowing of the urethra, causing urinary disorders. Therefore need further treatment.

Israeli medical centers with high efficiency used modern methods of radiation therapy, including intensity-modulated radiation therapy (IMRT) and brachytherapy. This ensures that the maximum amount of tumor tissue radiation with the least harm.

Brachytherapy, or internal radiation therapy

Brachytherapy uses small radioactive pellets, or "seeds," each the size of a grain of rice. They are placed into the prostate gland by visually monitoring the process via ultrasound, CT or MRI. By a computer program calculates the exact dose of radiation.

Indications for this type of prostate cancer treatment in Israel - the early stages of disease with low risk. Inefficient method after transurethral resection of the prostate (TURP), in case of problems with urination, with large volumes of the prostate tumor.

There are 2 types of brachytherapy. Both are carried out in the operating room, and anesthesia is required for each.

Permanent brachytherapy (dose low power)

Pellets from 40 to 100 with radioactive substances (iodine-125 or palladium-103, for example) by means of special needle is introduced into the gland. For a number of weeks or months, they emit low doses of radiation. Apply spinal anesthesia or general, you may need to stay overnight in the hospital.

Sometimes combined EBRT with brachytherapy if malignant cells have spread further.

Temporary brachytherapy (high dose rate)

This is a new technique. This type of prostate cancer treatment in Israel typically takes 2 days. Spend 3 treatments. With special needle mounted catheter, through which enters the radioactive iridium-192 or cesium-137 for a time of from five to fifteen minutes. Then this substance is removed and the catheter is removed after the last treatment. The advantage of the approach is that the nearby organs are affected. The urethra, the bladder, the colon remain intact.

Brachytherapy is also able to call:

  • intestinal problems (long term - less than 5%);
  • malfunction of the bladder: urinary incontinence, 1 in 3 men remain frequent urination;
  • erectile dysfunction: for a young age there is a high probability of recovery of sexual function after discontinuation of therapy.

Prevention and treatment of bone metastases in prostate cancer in Israel

Cancerous prostate cells first spread to nearby tissue and nearby lymph nodes, then hit the bone. The disease accompanied by pain, high levels of calcium, frequent fractures. All this can be dangerous to human life.

When the secondary outbreaks in the adjacent tissues of the main goal of treatment of prostate cancer in Israel - to reduce the rate of development of the disease and prevent bone loss. If it has already undergone pathological process, the main task - to relieve pain and other complications.

Hormone treatment and chemotherapy vaccine will help, but the following methods are more effective in a particular case.

bisphosphonates

Bisphosphonates are a group of drugs that help:

  • the problem of high levels of calcium;
  • relieve pain;
  • slow the growth and spread of metastases;
  • prevent fractures;
  • strengthen bones in men receiving hormone therapy.

In this disease most often used bisphosphonate Zoledronic acid (zoledronic acid). Performed intravenous injection once every three or four weeks. Men are also advised to take supplements containing vitamin D and calcium.

Bisphosphonates can cause side effects - flu-like symptoms, pain in the joints, bones. It is also possible kidney problems, so these drugs can not be taken for violations in the work of the kidneys.

A rare but very serious side effect of osteonecrosis of the jaw. Part of the jaw bone loses its blood supply and dies. This can lead to loss of teeth, the development of infections, open sores that do not heal and difficult to treat. There are a number of preventive measures to prevent such a state.

Denosumab

Denosumab (Xgeva ®, Prolia ®) helps to avoid fractures in prostate cancer metastases. He is able to prevent or delay fractures. According to studies, denosumab with zoledronic acid works best.

He was appointed as an injection every 4 weeks. It is carried out in parallel with calcium supplementation and vitamin D.

Undesirable effects of therapy include diarrhea, fatigue, nausea and, in rare cases - osteonecrosis of the jaw.

corticosteroids

Some studies suggest that corticosteroids (such as prednisone and dexamethasone) can relieve bone pain in patients and reduce the level of PSA.

External-beam radiation therapy

Irradiation can help to reduce pain in the bones, especially if the pain is limited to one or more areas of bone. For example, when a tumor on his spine in a number of cases it is possible to reduce the pressure on the spinal cord. Radiation therapy also facilitates other symptoms, reducing the size of tumors in other parts of the body.

radiopharmaceuticals

Radiopharmaceuticals containing radioactive elements. Are administered intravenously, after emit radiation in metastases, thereby killing the cancer.

In the treatment of metastases in Israel is mainly used in radiopharmaceutical 3:

  • Strontium-89 (Metastron ®)
  • Samarium-153 (Quadramet ®)
  • Radium-223 (Xofigo ®, previously called Alfaradin).

Unlike external beam radiotherapy treatment of all possible secondary foci simultaneously.

All three drugs relieve pain, but only radium-223 increases the life expectancy.

The main side effect is to reduce the number of blood cells as a consequence of an increased risk of infection and bleeding.

painkillers

When properly prescribed painkillers are very effective: ibuprofen, acetaminophen. Dependence on opiates is not a problem in the treatment of pain from cancer. Symptoms such as constipation and drowsiness usually eliminated by changing the dose or adding other medicines.

Take advantage of the services of professionals, do not waste your precious time! We can help solve health problems - organize treatment from the best doctors in the short term, at affordable cost.

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