thyroid cancer signsThyroid cancer called malignant tumor that develops from the cells directly to the gland itself. Thyroid gland is located at the front surface of the neck and is responsible for the production of important hormones for the body as tireoidin, triiodothyronine and calcitonin. The normal functioning of the thyroid gland depends on the body's metabolism, the level of glucose in the blood, brain development, growth of the organism as a whole, reproductive function, and many other vital processes.

Every year there is growth in the number of thyroid cancer cases. Some scholars associate this trend with the use of iodine deficiency in food and radiation exposure. Currently, the Israeli clinic thyroid cancer very successfully treated.

If you have been diagnosed with thyroid cancer, it is important to carry out the treatment by doctors with a high level of knowledge and experience. Our company, the center «Tlv.Hospital», could help in the organization of such treatment in Israel. Learn more about our services and capabilities in thepage .

Symptoms of thyroid cancer

Initially thyroid cancer are asymptomatic. When the tumor begins to grow, the patient can independently detect it by palpation or visual, as iron is close enough to the skin surface. We list the main features of thyroid cancer:

  • In the thyroid region, a nodal education.
  • Increase in the size of lymph nodes.
  • The increase in the gland itself.
  • Thickening of the neck.
  • Hyperthyroidism, hypothyroidism.
  • voice change.
  • Difficulty swallowing, sensation of a lump in the throat.
  • Pain in the front region of the neck.
  • The sudden rapid rise and consolidation of a benign node in the craw.

It is worth noting that the presence of nodules in the thyroid gland in more than 95% of cases are benign. Some of the symptoms of thyroid cancer in women have their own specifics. For example, a sign of the disease cancer can be considered a long-term approach is not desired pregnancy due to lack of hormones secreted by the thyroid gland.

Diagnosis of thyroid cancer in Israel

So, if you suspect thyroid cancer in his (its attributes), do not panic. The definitive diagnosis can only confirm an experienced oncologist and endocrinologist. Medical service en.thebestmedic.com.com offers you pass a comprehensive diagnosis of thyroid cancer in Israel. Our partners are the best clinics of Israel, which offer the following diagnostic techniques:

  • Lab tests.
  • US.
  • Doppler.
  • Fine-needle biopsy.
  • PET-CT, CT, MRI.
  • Isotopic scanning.

Israeli hospitals use for the diagnosis and treatment ofthe most modern equipment and the latest ultra-precise research methods. Thus eliminating the possibility of setting a wrong diagnosis.

Treatment of cancer of the thyroid gland in Israelthyroid cancer diagnosis

Oncology treatment in Israelis recognized around the world one of the best. With regard to malignant neoplasms of the thyroid gland, the treatment of cancer in Israel provided in early diagnosis indicates a positive result in more than 80% of cases. Doctor of the highest category determined by the upcoming course of treatment depending on the stage of cancer and the type of tumor (anaplastic carcinoma, papillary carcinoma, medullary cancer, follicular cancer). If the diagnosis of thyroid cancer metastasis has not yet begun, the likelihood of a full recovery is approximately 95%. We list the main methods of treatment of thyroid cancer in Israel:

  • Surgery.
  • Radioactive iodine.
  • Hormone.
  • Chemotherapy.
  • Radiation therapy.
  • Targeted treatment.
  • Palliative treatment.

With the patient runs a multidisciplinary team: the surgeon, oncologist, radiation oncologists, endocrinologist and other specialists.

Thyroid cancer in Israel is usually treated using a single method or a combination thereof. Selection is determined by several factors: the type and stage of the disease, the potential adverse effects, patient preference and choice, the general state of his health.

Israel clinics offer an innovative treatment of thyroid cancer, including minimally invasive and robotic surgery. Endoscopic thyroidectomy, application robot da Vinci, intraoperative neuromonitoring and intraoperative determination of parathyroid hormone (PTH) made oncological surgery thyroid safer and less invasive.

Surgical treatment of thyroid cancer in Israel

The operation removes the malignant tumor and part of the adjacent healthy tissue. Surgery is also called resection. This is the basic method of treatment in most cases. Depending on the size of the tumor operations are divided into several types:

  1. Lobectomy involves the removal of the share gland tumor.
  2. Partial thyroidectomy (subtotal) is performed in papillary or follicular cancer type 1 step. Performed resection share with malignancy and a small segment of the opposite side.
  3. Total thyroidectomy removes the full thyroid.

There are different approaches to thyroidectomy:

  1. Traditional or cavity, the surgeon makes a large incision at the base of the neck or in the middle part. This approach gives direct access to the thyroid gland.
  2. Endoscope approach involves the operation through several small incisions through special cameras and surgical instruments.
  3. The robotic approach. The surgeon makes the incisions in the axillary region or area in the thoracic cavity, and then uses robotic tools to complete the operation.

For each specific situation surgeons selected optimal approach and operation.

Lymph nodes form a network of glands throughout the body. The cancer can spread to them, increasing the size of nodes. If there is evidence or risk of penetration of the tumor process, it will be held lymphadenectomy - surgical procedure to remove the lymph nodes.

Surgery is also used, and in metastatic cancer. It does not eliminate the disease, but removing the diseased organ facilitates the patient's condition.

By surgery also resort to prevent medullary cancer. Performed a genetic test that determines - whether a person is a carrier of an abnormal gene RET. This gene causes the MEN syndrome, increasing the risk of medullary cancer. Children in such families usually check in a little aged. If you have the gene, doctors recommend to remove the entire thyroid gland that prevent cancer development. It is considered preferable to have surgery for children aged 5 years, sometimes even at the age of 6 months. After that required the administration of hormones for the rest of life.

Among the possible side effects of surgery note: damage nearby parathyroid glands (regulate calcium levels in the blood), hemorrhage, wound infection. If damage is applied laryngeal nerves, this leads to a temporary or permanent hoarseness, voice "aspirated".

After removal of the thyroid gland body stops synthesize triiodothyronine (T3) and tetraiodothyronine (thyroxine, T4). Appointed replacement therapy. It may be necessary vitamin D and calcium supplements due to injury of the parathyroid glands.

When the tumor can not be removed by surgery, it is called inoperable and recommend other therapies.

Israeli doctors have successfully applied these minimally invasive techniques for the treatment of thyroid cancer, as radio frequency and laser ablation.

Hormone therapy for thyroid cancer

When medullary, papillary and follicular cancer hormone therapy after surgery is needed. In addition to substitution treatment, which is required by the body, the thyroid hormone preparations contribute to slowing down the development of the rest of the differentiated cancer cells.

Replacement hormone is levothyroxine (Levothroid, Levoxyl, Synthroid, Tirosint, Unithroid and other names). His take pills every day for uninterrupted supply of the body. You should talk to your doctor about levothyroxine combination with other medications, including supplements - calcium or iron.

Thyroid drugs have side effects:

  1. This may be a rash or lose some hair in the first month of treatment.
  2. Hyperthyroidism - an excess of the hormone, which leads to the loss of body weight, chest pain, palpitations, arrhythmias, convulsions, diarrhea, loss of bone mass or osteoporosis.
  3. Hypothyroidism - hormone deficiency, provoking fatigue, dry skin and hair, weight gain, feeling cold.

For each patient, the type of tumor and its volume is required, and the dose of hormones. A doctor monitors the level of thyroid hormones in the blood through regular blood tests. If any symptoms occur, it may mean that the required adjustment of the dose.

radioiodine

Thyroid absorbs all the iodine, enters the body. Therefore, the type of radiation therapy called "radioactive iodine therapy" can find and destroy cancer cells that can not be removed by surgery, and those that have spread beyond the boundaries of the body. In this type of treatment of thyroid cancer in Israel is engaged in a radiation oncologist.

Radioactive iodine - option for the majority of cases papillary and follicular cancer types. a small test dose may be given, to determine whether the tumor cells to absorb I-131. Patients with medullary or anaplastic cancer is not treated in this manner.

I-131 is given in a liquid form or in pills. Depending on the dose and other factors of the patient may be hospitalized for 2-3 days. It is recommended to drink plenty of fluids to the drug has left the body faster. In just a few days most of the radiation comes out. The doctor will advise on the precautions in dealing with other people and children.

The process of preparation for thyroid cancer in Israel, such treatment requires adherence to a diet low in iodine 2-3 weeks. Also temporarily stopped hormone replacement therapy, or injections of recombinant TSH (Thyrogen). If you stop hormone treatment, you should expect side effects associated with hypothyroidism.

It is important to discuss the potential short-term and long-term consequences of radioactive iodine therapy. On the first day, some patients experience nausea and vomiting. Sometimes there is swelling and pain in places where radioactive iodine accumulates, for example, in the salivary glands. This can lead to kserotomii, lack of saliva in the oral cavity.

Large or cumulative doses of radioactive iodine can trigger infertility, especially in men. Women are advised to avoid pregnancy for at least one year after the treatment of thyroid cancer in Israel. There is a risk of recurrence. Sometimes require repeated treatments with iodine. However, there is a maximum total dose of radioactive iodine, beyond which treatment is stopped.

When the diagnosis is performed in Israel genetic testing. If diagnosed with medullary type of cancer, a blood test is performed to determine whether the patient is a carrier of the gene that causes oncology. When the test gives a positive result, children and parents of the patient being examined for the presence of the gene, because 90% of developing malignant disease.

External-beam radiation therapy

In the treatment of thyroid cancer in Israel will apply this method. This particular type of radiotherapy linear accelerators in which the ionizing radiation is supplied from the outside to the tumor to destroy malignant cells.

Calculated individually total cumulative dose, a schedule. The patient receives a certain number of procedures within the stipulated time. Radiation therapy for this diagnosis is usually performed on an outpatient basis, during the week, 5-6 weeks.

External radiation is used only in certain circumstances. For example, in the later stages of the disease when the body does not respond to radioactive iodine. Radiotherapy administered after surgery.

Potential side effects of this treatment are due to dose and treatment area. These include nausea, redness of the skin, cough, painful swallowing, hoarseness, fatigue.

Chemotherapy and targeted therapy

These types of treatment izarilskih clinics are also used. Chemotherapy is struggling with cancer using cytotoxic drugs. Selects regimens oncologist himioterapevt in cooperation with the command. Therapy consists of cycles, it involves the use of one or more drugs.

Chemotherapy in this case is a systemic treatment, circulate through the bloodstream, reaching and destroying abnormal cells throughout the body. The formulations may be ingested via intravenous (iv), capsules. Objectives of therapy:

  • to eliminate cancer cells after surgery;
  • slow tumor development;
  • ease symptoms of advanced cancer.

On the potential adverse consequences affect the dose of medicines, their number, the individual patient's response. Adverse actions include: diarrhea, loss of weight, fatigue, the likelihood of infection, gastrointestinal disorders (vomiting, nausea, loss of appetite).

Innovation in the treatment of thyroid cancer in Israel

Targeted therapy is aimed at specific genes, proteins, contribute to the development of tumors. Drugs targeted therapies block the growth of cancer cells without affecting healthy ones.

Recent studies show that not all tumors have the same goal. To find the most effective treatment for thyroid cancer in Israel, the doctor conducts genetic tests, identifying the genes, proteins, and other factors in the tumor. In addition, ongoing research aimed at the discovery of specific molecular targets in various types of thyroid cancer. Actively developed innovative methods.

In papillary and follicular cancer used two drugs:

  1. Sorafenib (Nexavar), approved by the FDA in 2013 year for the late stages of differentiation or recurrent cancer after failure of I-131 therapy. Common adverse effects include: skin rash, diarrhea, increased blood pressure, body weight loss.
  2. Lenvatinib (Lenvima, E7080), FDA approved in February 2015 years for later stages of differentiated thyroid cancer, which has not responded to the operation and / or I-131 therapy. Among the side effects are weight loss, high blood pressure, loss of appetite, diarrhea, nausea.

When medullary thyroid cancer using two drugs:

1.Vandetanib (Caprelsa, ZD6474), approved by the FDA in 2011, belongs to the group of tyrosine kinase inhibitor drugs. This is a standard treatment option for adults, when the tumor can not be removed by surgery, the disease progresses, or when any secondary foci in other parts of the body.

The medicine is taken daily, the daily dose - 300 mg. Among the side effects noted diarrhea and inflammation of the large intestine, skin rash, nausea, hypertension, headache, fatigue, loss of appetite, stomach pain. More serious possible consequences of acceptance - respiratory and cardiac disorders. At regular blood tests performed at the level of potassium, calcium, magnesium and TTG content for monitoring the body reaction to this drug.

2.Kabozantinib (Cometriq, XL184) - another tyrosine kinase inhibitor for metastatic medullary thyroid cancer, approved by the FDA in 2012. The recommended dose is 140 mg taken once a day. Among the unwanted consequences of receiving notice constipation, abdominal pain, hypertension, fatigue, hair color change, nausea, edema, disturbances in the colon.

Before starting the targeted treatment of cancer of the thyroid gland in Israel, the doctor will tell in detail about the possible side effects for each drug, as well as management techniques.

Cancer symptoms and management of side effects of treatment

Cancer and its treatment often provoke undesirable side effects. In addition to treating physicians task is to free the patient from the symptoms of the disease and the adverse effects of therapy.

The goal - to improve the condition and quality of life of the patient. The spectrum of such treatment a sufficiently wide, it includes medications, changes in diet, relaxation techniques, and other emotional support. Palliative treatment of thyroid cancer in Israel also contemplates the use of chemotherapy, surgery or radiotherapy.

The treatment options for thyroid cancer in Israel in stages

If the tumor is localized within the boundaries of the neck, hit both lobes of the thyroid gland, lymph nodes, surgery is generally the first procedure. Patients with advanced disease is treated by surgery, but first the other therapies may be employed queue. Clinical trials may recommend at any stage as a treatment option.

1 stage: surgery, hormone therapy, possibly radioactive iodine after surgery.

Stage 2: surgery, hormone therapy, possibly radioactive iodine after surgery.

Stage 3: hormone therapy, possibly radioactive iodine or external radiation therapy after surgery.

Step 4: surgery, hormone therapy, treatment with radioiodine, external radiation therapy, targeted therapy, chemotherapy.

Stage IV thyroid cancer

If the neoplastic process has gone beyond the boundaries of the prostate to other parts of the body and organs - in the bones or lungs, it is called metastatic or IV thyroid cancer stages. Also all anaplastic tumors classified as stage IV at diagnosis, regardless of the size of malignancy, localization and distribution.

It can be recommended plan for treatment of thyroid cancer in Israel that combines surgery, hormone therapy, radioactive iodine, external radiation, targeted therapy, and cytotoxic agents.

Remission and relapse opportunity

Remission - a condition where the disease is not detected in the body and there are no symptoms. Remission may be temporary or permanent. This situation is of concern in many patients. It is important that the patient understand that there is a risk of the disease returning and knew about the treatment options that can help.

A secondary tumor can arise at the same place (local relapse), next (regional recurrence) or in another area (distant metastasis).

If this happens, re-performed diagnosis, after which the doctor provides information about treatment options. Often the therapy program includes methods previously announced - surgery, radioactive iodine, hormone therapy, external radiation therapy, therapy with cytostatics. clinical trials can be recommended.

prices for treatment

Prices for treatment of thyroid cancer in Israel is now available at the moment there are many methods of treatment and diagnosis. Do not waste your time and go through the treatment in clinics in Israel. There are several ways of diagnosing the disease, which will go better for you than the individually selected different procedures.

Diagnosis 1:

  1. Consultation with a specialist endocrinologist - 550 dollars.
  2. blood tests - 550 dollars.
  3. US - 320 dollars.
  4. Revision of pathology - 680 dollars.

Total 2100 US dollars.

Diagnosis 2:

  1. Consultation with a specialist endocrinologist - 550 dollars.
  2. blood tests - 540 dollars.
  3. Biopsy - 1320 dollars.
  4. Histology - 680 dollars.

Total: 3100 USD.

In addition to diagnostic software, you can be treated with radioactive iodine by a physician:

  1. Consultation with a specialist endocrinologist - 550 dollars.
  2. US - 320 dollars.
  3. Scintigraphy - 560 dollars.
  4. Revision of pathology - 680 dollars.
  5. Scintigraphy of the whole body (one week) - in 1020 dollars.
  6. Ablation - 8770 dollars.

Total: 11910 USD.

Treatment:

  1. A biopsy of the thyroid gland histopathology - 2160 dollars.
  2. Fine-needle aspiration biopsy - 1385 dollars.
  3. Radioisotope study of the thyroid gland - 720 dollars.
  4. Hormones and thyroid Immunology - 430 dollars.
  5. Partial / total thyroidectomy - 7011 dollars.

After surgery, the patient is in the hospital under observation for several days. It is included in the operation, as well as the payment of royalties and operating surgeons and logistics services. Find out the answers to all your questions, you can, leaving a request through the request form.

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