cancer of the salivary gland symptomsCancer of the salivary gland is a very dangerous cancer. According to statistics, this type of cancer is very rare. The salivary glands are able to allocate a special secret - the saliva, which plays an important role in the human digestive system. a large number of salivary glands located in the mouth. Cancer typically affects large parotid salivary gland. To date, medicine has made tremendous progress in the treatment of this type of cancer. It is considered to be a very successful treatment for cancer of the salivary gland in Israel.

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Causes of salivary gland cancer

Causes of cancer in the salivary glands until the science is not known. But it was possible to establish a number of factors that increase the likelihood of a dangerous disease:

  • Smoking (it increases the salivation, congestion occurs gland);
  • Radiation exposure;
  • Hereditary factor.

The symptoms of salivary gland cancer

There are certain symptoms that may indicate the development of cancer in the salivary glands:

  • Swelling of various parts of the face: near the ears, on the cheeks, near the jaw;
  • Numbness of the face;
  • Possible paralysis of the face.

The presence of anxiety symptoms is a valid reason for passing examinations. Since early diagnosis significantly increases the chance of a full recovery.

Diagnosis of salivary gland cancer in Israel

The accuracy of the diagnosis depends on the quality of the subsequent course of treatment. Therefore, the Israeli clinic uses advanced equipment and modern methods of examination of patients. Typically, the following diagnostic methods are used:

  1. Examination and consultation oncologist.
  2. Ultrasonography. Ultrasound helps establish the location and size of the affected area of ​​the salivary gland.
  3. MR. During the session, the person is lying down in the machine stationary. All metal objects must be removed prior to the examination. Patients whose body weight is greater than 150 kg, MRI is not performed. Duration of examination is not more than an hour.
  4. Biopsy. Fence tumor cells from the affected portion of the prostate is carried out by using a fine needle and syringe.
  5. CT scan. The procedure allows to obtain an image of any desired portion of the patient's body. If necessary, the vein is introduced a certain amount of colorant. It is necessary to improve the quality of images. Examination of one zone lasts about 20 minutes. Dye yourself removed from the body of the patient for several days.

In that case, if the diagnosis is not confirmed the malignant nature of the tumor, it is still advisable to treat it. The fact that about eighty percent of the benign tumors eventually degenerate into malignant. The priority is a cancer treatment in Israel . Experts Consulting Center en.thebestmedic.com take care of all the questions on the organization of diagnosis and treatment of salivary gland cancer in Israel.

Treatment of cancer of the salivary glands in Israelcancer of the salivary gland treatment

Israeli medical institutions use advanced treatment methods and modern ultra-precise equipment. An integrated approach to the treatment of cancer of the salivary gland is characterized by very high efficiency. Therefore, treatment in Israel in most cases gives a positive result, every year thousands of people are returning to normal.

The treatment for this type of cancer depends on many factors - the size of a tumor, cancer, localization, health condition of the patient, etc. Of particular importance is the stage of the disease.. Customary to distinguish four stages of cancer of the salivary glands:

1st stage - a tumor reaches a maximum size of 2 cm is not beyond the boundaries of the prostate;

2nd stage - the size of tumors from 2 to 4 cm, not beyond the body;

3rd step - tumor size of about 4 cm, begins to grow into the adjacent tissues and lymph nodes;

4th stage - tumor invades the skin, nerves, bone metastases begin.

In practice uses the following methods of treatment of cancer of the salivary glands in Israel.

Surgical treatment of cancer of the salivary glands

Operation - the main method of treatment of cancer of the salivary glands in Israel. The choice of surgical intervention due to the tumor site and stage position (as the disease has spread in the body far).

Surgery for cancer of the salivary gland is conducted specialized team of doctors who have experience in carrying out this type of surgery:

  • Maxillofacial surgeon.
  • ENT surgeon.
  • Consultant in Restorative Dentistry.
  • Plastic Surgeon.
  • Anesthetist.
  • Nurse.

The Israeli hospitals conducted specialized surgical intervention: the parotid, submandibular and sublingual glands.

Israel's clinics use the latest technology in the treatment, including radiation therapy or intensity-modulated stereotactic radiosurgery, which provide a strong flux of radiation malignant cells, limiting the negative impact on surrounding healthy tissues - the eyes, optic nerves, brain and spinal cord.

Surgery of the parotid gland

The parotid glands are divided into two parts - superficial and deep. Between them is the facial nerve, which is important for activities such as closing of the eyes, nose and lips shrinkage movements.

If a tumor is found only in the superficial lobe, the tumor has a low degree of malignancy may only delete it. Such an operation for cancer, salivary gland called parotidektomiya surface. If the tumor has struck a deep interest or both, need to be fully resection of the parotid gland. Held a total parotidektomiya.

The surgeon makes an incision on the front of the ear, down the line to the cheek and along the jaw line. It will remain a scar shaped like the English letter S.

This is a complicated operation, since the facial nerve passes through the center of the gland. Wherever possible, the surgeon will try to remove only the iron and keep the facial nerve. Most people have seen a good recovery and a full range of facial movements after surgery for cancer of the salivary gland. If the doctor has to remove part or all of the facial nerve, it is located next to transplant nerve or nerve of the calf muscle.

At the parotid gland surgeon removes some of the surrounding tissue. This is necessary to resect all of the cancer cells and reduce the likelihood of relapse. Rarely requires removal of part of the jaw. Also may need resection of nearby lymph nodes.

Surgery to the submandibular glands

If the tumor occurs in one of the submandibular gland, the surgeon will remove the full authority, and some surrounding tissue to reduce the likelihood of relapse.

For suspected of having cancer cells in the lymph nodes, they are also resected. Occasionally there is a need to remove some of the jaw bone.

Next to the submandibular gland has 3 nerves that control the lips and the tongue. The surgeon will try to remove the gland without damaging these nerves. Sometimes it happens, in most cases, the problems are temporary in nature, as a rule, mobility is completely restored within a few weeks. Sometimes several months is required.

Before the operation for cancer of the salivary glands surgeon will explain what will be specifically deleted, as well as give information about possible side effects. After surgery, the scar will be located below the jaw line.

Surgery sublingual salivary glands

Under the tongue are two sublingual gland. The surgeon makes an incision in the oral cavity, removes iron and some surrounding tissue, sometimes - part of the jawbone. This reduces the risk of the disease returning.

Along the sublingual gland passes nerve, which controls sensation and taste of the sides of the tongue. In some cases, it required its removal. Or it may be damaged during the operation. After that insemination can be observed on the other side of language. Usually this is a temporary phenomenon, which lasts from several weeks to a couple months.

There is a risk of the presence of cancer cells in nearby lymph nodes that require their resection. This can mean an additional cut in the side of the neck.

Removal of lymph nodes in the treatment of salivary gland cancer in Israel

Lymph nodes in the neck resected in the following situations:

  • If the tumor has a high degree of malignancy.
  • Swollen lymph nodes, marked edema.
  • Diagnostic tests indicate the presence of cancer cells in them.

Selective neck dissection involves the removal of some lymph nodes. When cancer affects more than one site, all resected lymph nodes on the affected side of the neck. Such an operation is called a modified radical neck dissection. If the neoplastic process affect other nearby structures, the surgeon removes these structures - conducts a complete neck dissection. It includes the sternocleidomastoid muscle, accessory nerve, internal jugular vein. This operation helps to stop the spread or return of cancer.

Israeli doctors prefer minimally invasive methods. Surgery to remove the salivary gland is quite complicated, because there are several near important nerves. Israeli surgeons have extensive experience in minimally invasive operations that provide a better cosmetic effect and fewer unwanted effects.

Reconstructive surgery in the treatment of cancer of the salivary glands

In general, most people with the disease are removed only salivary glands. In rare cases, the disease process affects the bones or the deeper the surrounding tissue. If this occurs, it requires surgery to remove the tumor and recovery of the mouth and jaw. The goal of surgery - to restore the appearance and function - food intake, fluid speech.

Select the type of the operation is due to the position of the tumor and its spread. You may need to take only the skin or tissue from other parts of the body for the reconstruction. Some people are in need of dental implants to replace a portion of the jaw and teeth.

If you really need reconstructive surgery, the doctor will give full course of the patient's case, tell about the possible side effects of surgery. It is important to ask the expert all the questions.

Before the operation, it will require a number of tests that may include:

  • Blood tests.
  • Chest X-ray or CT scan.
  • Electrocardiogram (ECG), ECG with load.
  • Breath tests.

salivary gland cancer radiotherapy in Israel

In the struggle with cancer Radiotherapy uses ionizing radiation. It may be designated as a basic method, and also in combination with surgery.

After surgery recommended irradiation, if the tumor has a high degree of malignancy, or it has spread to the lymph nodes. Radiotherapy reduces the risk of the disease returning.

Primary treatment for salivary gland cancer radiation therapy is used in the following cases:

  1. If the tumor is located in a place where it is difficult to remove.
  2. When the tumor is too large, so it can be resected.
  3. There are other health problems.
  4. To control the symptoms of metastatic cancer.

In the treatment of salivary gland cancer in Israel use external radiation, guided by a linear accelerator to the affected area. If radiation therapy is prescribed after the surgery, the procedure is performed daily, on weekdays, within 1-1.5 months.

When radiotherapy recommended as the main method, the number of treatments depends on the individual characteristics of the disease. In metastatic malignancy therapy continues basically four weeks.

Before the treatment of cancer of the salivary gland team carefully plans radiotherapists radiotherapy calculates total radiation dose and treatment area. Performed CT, MRI or PET.

To ensure the immobility of the head is made individually mask, it ensures that the radiation precisely reach the affected area.

When you select a program for treating cancer of the salivary glands in Israel found its personalized approach. therapy plan is determined based on the precision of genetic tests that detect certain types of tumor mutations.

Possible side effects

Side effects usually develop gradually. Most people have observed some unwanted effects, which are mainly deteriorated by the end of the course. 2-3 weeks after completion of therapy condition gradually returning to normal. It can take up to 6 weeks.

Typically, radiation therapy is fatigue, redness and inflammation in the treatment area. It is important to know that you should not use any lotions, powders and creams in the treatment area without the recommendation of doctors.

Dryness in the mouth

The salivary glands produce saliva, which moistens the mouth and throat; contributes to the preservation of dental health; It helps swallowing, digestion, improve mouthfeel. Radiation therapy stops the production of saliva. With the patient communicates doctor prior to irradiation.

Usually suffer only glands that are exposed to radiation. On the other hand, they continue to function properly. It is extremely rare in humans observed the constant dryness in the mouth after the treatment of salivary gland cancer.

If you have problems with dryness are issued special drugs that help retain moisture, reduce the risk of infections and tooth decay. Needs to be regularly examined by a dentist.

Most people saliva synthesis resumed within 4-8 weeks after completion of radiotherapy.

Inflammation of the throat and mouth

In the mouth and throat may develop painful ulcers. If they cause a lot of pain, painkillers are assigned, for example, morphine. The physician may recommend gel Gelclair, forming a protective barrier in the oral cavity, reducing soreness. Thus, it will be easier to take food or liquid.

Changes in taste

Radiation therapy to the head and neck often affects the taste. It may be lost taste any strange taste. Often people notice a metallic taste after radiotherapy, and some types of chemotherapy. Loss of taste decreases appetite.

loss of hearing

Radiotherapy of parotid gland can cause damage to the inner ear and hearing loss.

Problems with teeth

Irradiation of oral cavity can cause caries. There will be a need for more frequent visits to the dentist. Fluoridation helps protect teeth, gargle with a special liquid is used twice a day. Any dental work can be carried out only after the interaction with the consultant for restorative dentistry. If it becomes necessary to remove some teeth after exposure, this should be done under the supervision of the maxillofacial surgeon.

Chemotherapy in the treatment of cancer of the salivary glands in Israel

The basic method of treatment of this disease is surgery. In the initial stages do not apply chemotherapy. Currently, there is insufficient evidence that treatment with cytotoxic drugs reduces the risk of cancer. However, chemotherapy is used in the metastatic process, as well as contraindications to surgery or radiotherapy.

Used in the treatment of cancer of the salivary glands of the following drugs:

  • cisplatin
  • carboplatin
  • cyclophosphamide
  • doxorubicin
  • methotrexate
  • paclitaxel

Most cytostatics cause certain side effects, are more likely to say:

  • nausea;
  • reducing the number of blood cells;
  • fatigue;
  • changes in the kidney;
  • in lung function.

In the appointment of chemotherapy it is important to inform your doctor about bioadditives taken. There is no sufficient information about their interaction with cytostatic agents. Some of them may reduce the effectiveness of chemotherapy.

Prognosis of cancer of the salivary glands

Here is a statistic based on various sources for guidance. The term "five-year survival rate" means the number of participants in clinical studies who were alive 5 years after treatment.

Cancer salivary glands - a rare disease, accounting for approximately 1% of all malignant tumors. Most of the tumors of the salivary glands are benign.

GRANTS 3 main and the largest salivary gland and hundreds of small and insignificant. Cancer develops as a rule, in the largest - parotid gland - this is 80% of cases. 2 out of 10 cases of salivary gland cancers occur in submandibular and sublingual glands. Less than 1 out of 10 cases develop in the minor salivary glands.

There are many different types of cancer of the salivary glands, the most common of which - mukoepidermoidnaya carcinoma - 25-35% of all cases.

statistics Summary

As with many types of cancer, cancer of the salivary glands forecast due to stage of disease, the degree of malignancy and the type of cancer.

In general, for all types and stages of cancer of the salivary glands was observed in 75% of women and 60% men - 10-year survival rate after diagnosis.

Prospects for the type of salivary gland cancer

There are many different types of this type of cancer, some of them very rare. This creates difficulties for the analysis and conclusions, as they are based on the results involving a small number of people.

There 5-year survival rate for the following diseases:

  1. When adenoid cystic carcinoma - in 78% of patients.
  2. When mukoepidermoidnoy carcinoma - 80%. If the tumor has a high degree of malignancy - 20-40% of patients.
  3. When acinar cell carcinoma - at 80-90%.
  4. When adenocarcinoma tumors and mixed - 50%.
  5. When squamous cell carcinoma - 25%.

Prospects for Research on Cancer stages major salivary glands. For early-stage prospects are generally quite good.

  1. In the first stage - in 90% of patients - 10-year survival.
  2. In the second stage - in 75% of patients - five-year survival rate, at 70% - 10-year survival.
  3. In the third stage - 70% - 5-year survival rate, at 50% - 10-year survival.
  4. On a quarter-stage - the worst prognosis. In 40% - 5-year survival rate, 30% - a 10-year survival.

Statistics for malignant tumors of minor salivary glands

This is a very rare type of cancer, accounting for 1%. Accordingly, the statistics here to find more complex figures - less reliable. On average, 50-60% - a 10-year survival.

  • In step 1 - 80% - 5-year survival.
  • At step 2 - 70% - 5-year survival.
  • In step 3 - 60% - 5-year survival.
  • In step 4 30% - 5-year survival.

It is important to remember that there is no statistical data, based on which it can be assumed events for each case. The rate of development of the same disease is different in different people. Many factors determine treatment and prognosis in cancer of the salivary gland. The best option may be given only by the attending physician.

After the treatment of salivary gland cancer full rehabilitation helps to achieve maximum effect.

Price for treatment

A rare oncology successfully treated in Israel. Do not hesitate with the decision to go for treatment, the sooner you start treatment, the better the chance for recovery. Prices for treatment of salivary gland cancer in Israeli hospitals is lower than in European countries. Integrated diagnostic software will allow the doctor to accurately determine the treatment plan.

Diagnostics:

  1. Advisory welcome oncologist - $ 600.
  2. US - $ 390.
  3. A complete blood count - $ 540.
  4. Tumor markers - 120 dollars.
  5. Biopsies - 680 dollars.
  6. PET-CT - 1670 dollars.

The total sum of 4000 dollars.

Treatment options:

  1. Salivary gland biopsy - 10120 dollars.
  2. Resection of parotid gland - 38500 dollars.
  3. Chemotherapy - 1080 dollars.
  4. Radiotherapy -140 dollars.
  5. Immunotherapy - 2300 dollars.

treatment options to achieve the greatest effect, doctors often combine. But individual treatment plan for each patient, and the price may be different. The cost of the operation is included in the determination and payment specialist clinic fees. Learn more about the price and the procedures you can call or leave your request on the site.

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